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实质组织用于评估一氧化碳中毒的可靠性如何?一项初步研究。

How reliable are parenchymal tissues for the evaluation of carbon monoxide poisoning? A pilot study.

作者信息

Casali Michelangelo Bruno, Sironi Luca, Caligara Marina, Blandino Alberto, Circelli Silvia, Schiavi Davide, Cattaneo Cristina

机构信息

Institute of Forensic Medicine of Milan, Università degli Studi di Milano, v. L. Mangiagalli 37, Milano, Italy.

出版信息

J Forensic Sci. 2015 Mar;60(2):488-94. doi: 10.1111/1556-4029.12664. Epub 2014 Dec 30.

DOI:10.1111/1556-4029.12664
PMID:25557973
Abstract

Dealing with burnt bodies, the forensic pathologist must first of all answer the question whether the victim was alive at the moment of the fire. This study aims at clarifying whether some human solid tissues may be reliably used for the forensic diagnosis of Co poisoning on burnt bodies providing no collectable blood during the autopsy. From 34 selected cases, both cardiac blood and parenchymal samples were collected to perform CO-oxymeter, spectrophotometry, and gas chromatography tests: blood CO estimations (blood COHb% and blood[CO]) and parenchymal[CO] values have been compared with special focus on R values. The solid tissues having the best correlations with blood CO amount turned out to be the lung (R 0.84), the liver (R 0.83), the kidney (R 0.79), and the spleen (R 0.92).

摘要

在处理烧焦尸体时,法医病理学家首先必须回答受害者在火灾发生时是否还活着这个问题。本研究旨在阐明在尸检时无法采集到血液的情况下,某些人体实体组织是否可可靠地用于烧焦尸体一氧化碳中毒的法医诊断。从34例选定病例中,采集了心脏血液和实质样本,进行一氧化碳血氧计、分光光度法和气相色谱测试:比较了血液一氧化碳估计值(血液碳氧血红蛋白百分比和血液[CO])和实质[CO]值,并特别关注R值。结果发现,与血液一氧化碳含量相关性最好的实体组织是肺(R 0.84)、肝脏(R 0.83)、肾脏(R 0.79)和脾脏(R 0.92)。

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