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牙种植体纳米表面改性技术

Techniques for dental implant nanosurface modifications.

作者信息

Pachauri Preeti, Bathala Lakshmana Rao, Sangur Rajashekar

机构信息

Department of Prosthodontics, Faculty of Dentistry, Rama Dental College-Hospital & Research Centre, Kanpur, India.

Department of Prosthodontics, Faculty of Dentistry, Lenora Institute of Dental Sciences, Andhra Pradesh, India.

出版信息

J Adv Prosthodont. 2014 Dec;6(6):498-504. doi: 10.4047/jap.2014.6.6.498. Epub 2014 Dec 17.

Abstract

PURPOSE

Dental implant has gained clinical success over last decade with the major drawback related to osseointegration as properties of metal (Titanium) are different from human bone. Currently implant procedures include endosseous type of dental implants with nanoscale surface characteristics. The objective of this review article is to summarize the role of nanotopography on titanium dental implant surfaces in order to improve osseointegration and various techniques that can generate nanoscale topographic features to titanium implants.

MATERIALS AND METHODS

A systematic electronic search of English language peer reviewed dental literature was performed for articles published between December 1987 to January 2012. Search was conducted in Medline, PubMed and Google scholar supplemented by hand searching of selected journals. 101 articles were assigned to full text analysis. Articles were selected according to inclusion and exclusion criterion. All articles were screened according to inclusion standard. 39 articles were included in the analysis.

RESULTS

Out of 39 studies, seven studies demonstrated that bone implant contact increases with increase in surface roughness. Five studies showed comparative evaluation of techniques producing microtopography and nanotopography. Eight studies concluded that osteoblasts preferably adhere to nano structure as compared to smooth surface. Six studies illustrated that nanotopography modify implant surface and their properties. Thirteen studies described techniques to produce nano roughness.

CONCLUSION

Modification of dental osseous implants at nanoscale level produced by various techniques can alter biological responses that may improve osseointegration and dental implant procedures.

摘要

目的

在过去十年中,牙种植体已取得临床成功,但其主要缺点与骨结合有关,因为金属(钛)的特性与人体骨骼不同。目前的种植手术包括具有纳米级表面特征的骨内型牙种植体。这篇综述文章的目的是总结钛牙种植体表面纳米形貌在改善骨结合方面的作用,以及可在钛种植体上产生纳米级形貌特征的各种技术。

材料与方法

对1987年12月至2012年1月发表的英文同行评议牙科文献进行系统的电子检索。检索在Medline、PubMed和谷歌学术中进行,并辅以对选定期刊的手工检索。101篇文章被指定进行全文分析。根据纳入和排除标准选择文章。所有文章均根据纳入标准进行筛选。39篇文章被纳入分析。

结果

在39项研究中,7项研究表明骨-种植体接触随着表面粗糙度的增加而增加。5项研究对产生微形貌和纳米形貌的技术进行了比较评估。8项研究得出结论,与光滑表面相比,成骨细胞更倾向于附着在纳米结构上。6项研究表明纳米形貌改变了种植体表面及其性能。13项研究描述了产生纳米粗糙度的技术。

结论

通过各种技术在纳米尺度上对牙骨种植体进行改性,可以改变生物学反应,从而可能改善骨结合和牙种植手术。

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