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本文引用的文献

1
Nano hydroxyapatite-coated implants improve bone nanomechanical properties.纳米羟基磷灰石涂层植入物可改善骨纳米力学性能。
J Dent Res. 2012 Dec;91(12):1172-7. doi: 10.1177/0022034512463240. Epub 2012 Oct 8.
2
Bone bonding at natural and biomaterial surfaces.天然及生物材料表面的骨结合
Biomaterials. 2007 Dec;28(34):5058-67. doi: 10.1016/j.biomaterials.2007.07.049. Epub 2007 Aug 13.
3
Influence of a nanometer-scale surface enhancement on de novo bone formation on titanium implants: a histomorphometric study in human maxillae.纳米级表面增强对钛种植体上新生骨形成的影响:一项在人类上颌骨的组织形态计量学研究
Int J Periodontics Restorative Dent. 2007 Jun;27(3):211-9.
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Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands.细胞铺展和粘着斑动力学受整合素配体间距的调节。
Biophys J. 2007 Apr 15;92(8):2964-74. doi: 10.1529/biophysj.106.089730. Epub 2007 Feb 2.
5
Applications of nanotechnology in orthopaedics.纳米技术在骨科中的应用。
Clin Orthop Relat Res. 2007 Mar;456:243-9. doi: 10.1097/BLO.0b013e31803125f4.
6
Nanobiomaterial applications in orthopedics.纳米生物材料在骨科中的应用。
J Orthop Res. 2007 Jan;25(1):11-22. doi: 10.1002/jor.20305.
7
Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2.纳米相氧化锌和二氧化钛对成骨细胞功能有增强作用,对表皮葡萄球菌功能有抑制作用。
J Biomed Mater Res A. 2006 Sep 1;78(3):595-604. doi: 10.1002/jbm.a.30789.
8
Osteoblast-like cells are sensitive to submicron-scale surface structure.成骨样细胞对亚微米级表面结构敏感。
Clin Oral Implants Res. 2006 Jun;17(3):258-64. doi: 10.1111/j.1600-0501.2005.01195.x.
9
Using hydroxyapatite nanoparticles and decreased crystallinity to promote osteoblast adhesion similar to functionalizing with RGD.使用羟基磷灰石纳米颗粒并降低结晶度以促进成骨细胞黏附,类似于用RGD进行功能化。
Biomaterials. 2006 May;27(14):2798-805. doi: 10.1016/j.biomaterials.2005.12.008. Epub 2006 Jan 23.
10
Oral implant surfaces: Part 1--review focusing on topographic and chemical properties of different surfaces and in vivo responses to them.口腔种植体表面:第1部分——聚焦于不同表面的形貌和化学性质及其体内反应的综述
Int J Prosthodont. 2004 Sep-Oct;17(5):536-43.

纳米表面——植入物的未来。

Nanosurface - the future of implants.

作者信息

Thakral Gk, Thakral Rashmi, Sharma Neeraj, Seth Jyotsana, Vashisht Pallavi

机构信息

Professor, Department of Prosthodontics, SDCH , Rishikesh, India .

Professor, Department of Periodontology, SDCH , Rishikesh, India .

出版信息

J Clin Diagn Res. 2014 May;8(5):ZE07-10. doi: 10.7860/JCDR/2014/8764.4355. Epub 2014 May 15.

DOI:10.7860/JCDR/2014/8764.4355
PMID:24995264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4080085/
Abstract

Nanotechnology is a relatively newer field of science that is finding enormous scope in the dental & medical science. Use of endosseous dental implant surfaces having nano-scale topography is fast becoming part of modern implantology. The purpose of this review is to discuss and understand the role of nanoscale surface modification of titanium materials for the purpose of improving various phases of implantology including osseointegration. Nanotechnology equips bioengineers with newer ways of interacting with relevant biological processes. On the other hand, the field of nanotechnology provides means of understanding and achieving cell specific functions. An understanding of the role of nano-topography leads to the significant osseointegration modulations by nanoscale modification of the implants surface. Use of nanotechnology to modify the topography of titanium endosseous implant can drastically improve cellular and tissue responses that may benefit osseointegration and dental implant procedures.

摘要

纳米技术是一个相对较新的科学领域,在牙科和医学领域有着广阔的应用前景。具有纳米级形貌的骨内牙种植体表面的应用正迅速成为现代种植学的一部分。本综述的目的是讨论和理解钛材料纳米级表面改性在改善包括骨整合在内的种植学各个阶段中的作用。纳米技术为生物工程师提供了与相关生物过程相互作用的新方法。另一方面,纳米技术领域提供了理解和实现细胞特定功能的手段。对纳米形貌作用的理解可通过对种植体表面进行纳米级改性实现显著的骨整合调节。利用纳米技术改变钛骨内种植体的形貌可大幅改善细胞和组织反应,这可能有益于骨整合和牙种植手术。