Nordenström B E
Department of Diagnostic Radiology, Karolinska Hospital, Stockholm, Sweden.
Am J Clin Oncol. 1989 Dec;12(6):530-6.
Percutaneous placement of an intraneoplasmic electrode in pulmonary metastases of three patients with extrathoracic primary cancers permitted electrochemical treatment of these lesions. These reacted variably to anodic and cathodic electrodes. One breast cancer metastasis disappeared after treatment with the anodic field. A small metastasis from a cancer of the urinary bladder was found to be resistant to both anodic and cathodic fields despite large doses of current. Two large metastases of about equal size from the leiomyosarcoma of the uterus showed progression of the cranial anodic neoplasm but regression of the caudal cathodic neoplasm. At reversed polarity the cathodic neoplasm showed a tendency to regress and the caudal neoplasm continued to disappear. It appears that different neoplasms may show a variable response to anodic or cathodic fields or may show poor sensitivity to both fields.
对3例胸外原发性癌症患者肺转移灶经皮植入内质电极，可对这些病灶进行电化学治疗。这些病灶对阳极和阴极电极的反应各不相同。1例乳腺癌转移灶经阳极电场治疗后消失。1例来自膀胱癌的小转移灶尽管施加了大剂量电流，但对阳极和阴极电场均耐药。2例来自子宫平滑肌肉瘤的大小大致相等的大转移灶，显示颅侧阳极肿瘤进展，而尾侧阴极肿瘤消退。当极性反转时，阴极肿瘤有消退趋势，尾侧肿瘤继续消失。似乎不同的肿瘤对阳极或阴极电场可能表现出不同的反应，或者对两者均表现出低敏感性。
