Quinlivan E Byrd, Fletcher Jason, Eastwood Elizabeth A, Blank Arthur E, Verdecias Niko, Roytburd Katya
1 Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
AIDS Patient Care STDS. 2015 Jan;29 Suppl 1(Suppl 1):S11-9. doi: 10.1089/apc.2014.0277.
The WOC Initiative is a prospective study of 921 women of color (WOC) entering HIV care at nine (three rural, six urban) sites across the US. A baseline interview was performed that included self-reported limitation(s) in activity, health conditions, and the CDC's health-related quality of life measures (Healthy Days). One-third of the WOC reported limiting an activity because of illness or a health condition and those with an activity limitation reported 13 physically and 14 mentally unhealthy days/month, compared with 5 physically and 9 mentally unhealthy days/month in the absence of an activity limitation. Age was associated with a three- to fourfold increased risk of an activity limitation but only for WOC in the urban sites. Diabetes was associated with a threefold increased risk of a limitation among women at rural sites. Cardiac disease was associated with a six- to sevenfold increased risk of an activity limitation for both urban and rural WOC. HIV+ WOC reported more physically and mentally unhealthy days than the general US female population even without an activity limitation. Prevention and treatment of diabetes and cardiovascular disease will need to be a standard part of HIV care to promote the long-term health and HRQOL for HIV-infected WOC.
妇女健康倡议（WOC Initiative）是一项针对921名有色人种女性（WOC）的前瞻性研究，这些女性在美国九个地点（三个农村、六个城市）接受艾滋病毒治疗。进行了一次基线访谈，内容包括自我报告的活动受限情况、健康状况以及美国疾病控制与预防中心的健康相关生活质量指标（健康天数）。三分之一的有色人种女性报告称因疾病或健康状况而限制了一项活动，而那些有活动受限情况的女性每月报告有13天身体不健康和14天精神不健康，相比之下，没有活动受限的女性每月有5天身体不健康和9天精神不健康。年龄与活动受限风险增加三到四倍有关，但仅适用于城市地区的有色人种女性。糖尿病与农村地区女性活动受限风险增加两倍有关。心脏病与城市和农村有色人种女性活动受限风险增加六到七倍有关。即使没有活动受限，感染艾滋病毒的有色人种女性报告的身体和精神不健康天数也比美国普通女性人群更多。糖尿病和心血管疾病的预防和治疗需要成为艾滋病毒治疗的标准组成部分，以促进感染艾滋病毒的有色人种女性的长期健康和健康相关生活质量。
