Lou Z C
Zhen Ci Yan Jiu. 1989;14(3):319-22, 314.
In conscious rabbits, injection of cAMP (100 micrograms in 100 microliters, icv) elicited high-amplitude and high-frequency epileptiform seizure pattern of ECoG. The epileptic waves were inhibited by electro-acupuncturing bilateral "Zusanli" Points. During and after the cessation of electro-acupuncture the frequency, amplitude and duration of epileptiform discharges decreased significantly, the seizure waves even disappeared completely. The frequency and amplitude of epileptic waves showed significant difference in comparison with those of the non-electroacupuncture group (p less than 0.001 and p less than 0.01 respectively), the duration of epileptic waves shortened by 58.18-66.88%. The results suggested that electroacupuncture has antiepileptic action on c-AMP induced experimental epileptic seizure.
在清醒兔中，脑室内注射环磷酸腺苷（100微升含100微克，icv）可诱发脑电图（ECoG）出现高振幅和高频癫痫样发作模式。电针双侧“足三里”穴可抑制癫痫波。在电针期间及电针停止后，癫痫样放电的频率、振幅和持续时间均显著降低，癫痫波甚至完全消失。与非电针组相比，癫痫波的频率和振幅有显著差异（分别为p<0.001和p<0.01），癫痫波的持续时间缩短了58.18% - 66.88%。结果提示电针对于环磷酸腺苷诱导的实验性癫痫发作具有抗癫痫作用。
