Center for Learning Health Care, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA.
J Pers Med. 2012 Dec 27;3(1):1-13. doi: 10.3390/jpm3010001.
Cancer care is often inconsistently delivered with inadequate incorporation of patient values and objective evidence into decision-making. Utilization of time limited trials of care with predefined decision points that are based on iteratively updated best evidence, tools that inform providers about a patient's experience and values, and known information about a patient's disease will allow superior matched care to be delivered. Personalized medicine does not merely refer to the incorporation of genetic information into clinical care, it involves utilization of the wide array of data points relevant to care, many of which are readily available at the bedside today. By pushing uptake of personalized matching available today, clinicians can better address the triple aim of improved health, lowers costs, and enhanced patient experience, and we can prepare the health care landscape for the iterative inclusion of progressively more sophisticated information as newer tests and information become available to support the personalized medicine paradigm.
癌症护理的提供往往不一致，在决策中未能充分纳入患者的价值观和客观证据。利用有时间限制的护理试验，这些试验具有基于迭代更新的最佳证据的预定决策点、为提供者提供有关患者体验和价值观的工具，以及有关患者疾病的已知信息，将允许提供更好的匹配护理。个性化医疗不仅仅是指将遗传信息纳入临床护理，它还涉及利用与护理相关的广泛数据点，其中许多数据点今天在床边就可以获得。通过推动今天可用的个性化匹配的采用，临床医生可以更好地实现改善健康、降低成本和增强患者体验的三重目标，我们可以为迭代纳入越来越复杂的信息做好准备，因为新的测试和信息可以支持个性化医疗范式。
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