GGZ inGeest, Amsterdam, The Netherlands; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands; EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands; PsyQ, Parnassia Groep, The Hague, The Netherlands;
GGZ inGeest, Amsterdam, The Netherlands; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.
Eur J Psychotraumatol. 2014 Oct 14;5:23613. doi: 10.3402/ejpt.v5.23613. eCollection 2014.
Effective first-line treatments for posttraumatic stress disorder (PTSD) are well established, but their generalizability to child abuse (CA)-related Complex PTSD is largely unknown.
A quantitative review of the literature was performed, identifying seven studies, with treatments specifically targeting CA-related PTSD or Complex PTSD, which were meta-analyzed, including variables such as effect size, drop-out, recovery, and improvement rates.
Only six studies with one or more cognitive behavior therapy (CBT) treatment conditions and one with a present centered therapy condition could be meta-analyzed. RESULTS indicate that CA-related PTSD patients profit with large effect sizes and modest recovery and improvement rates. Treatments which include exposure showed greater effect sizes especially in completers' analyses, although no differential results were found in recovery and improvement rates. However, results in the subgroup of CA-related Complex PTSD studies were least favorable. Within the Complex PTSD subgroup, no superior effect size was found for exposure, and affect management resulted in more favorable recovery and improvement rates and less drop-out, as compared to exposure, especially in intention-to-treat analyses.
Limited evidence suggests that predominantly CBT treatments are effective, but do not suffice to achieve satisfactory end states, especially in Complex PTSD populations. Moreover, we propose that future research should focus on direct comparisons between types of treatment for Complex PTSD patients, thereby increasing generalizability of results.
创伤后应激障碍(PTSD)的有效一线治疗方法已得到充分确立,但它们在与虐待儿童(CA)相关的复杂性 PTSD 中的普遍性尚不清楚。
对文献进行了定量综述,确定了七项专门针对 CA 相关 PTSD 或复杂性 PTSD 的治疗研究,并对其进行了荟萃分析,包括效应大小、辍学率、恢复率和改善率等变量。
只有六项研究有一个或多个认知行为疗法(CBT)治疗条件,一项研究有一个以现在为中心的治疗条件,可以进行荟萃分析。结果表明,CA 相关 PTSD 患者受益于较大的效应大小和适度的恢复和改善率。包含暴露疗法的治疗方法显示出更大的效应大小,尤其是在完成者分析中,尽管在恢复和改善率方面没有发现差异结果。然而,在与 CA 相关的复杂性 PTSD 研究的亚组中,结果最不理想。在复杂性 PTSD 亚组中,与暴露疗法相比,情绪管理对恢复和改善率的影响更大,辍学率更低,尤其是在意向治疗分析中。
有限的证据表明,主要的 CBT 治疗方法是有效的,但不足以达到令人满意的终末状态,尤其是在复杂性 PTSD 人群中。此外,我们建议未来的研究应侧重于复杂性 PTSD 患者的不同治疗类型之间的直接比较,从而提高结果的普遍性。