Department of Pediatric Hematology, Emma Children's Hospital Academic Medical Center, and Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Department of Pediatric Hematology, Emma Children's Hospital Academic Medical Center, and.
Blood. 2015 Feb 12;125(7):1073-7. doi: 10.1182/blood-2014-05-536060. Epub 2015 Jan 6.
The etiology of pediatric venous thromboembolic disease (VTE) is multifactorial, and in most children, 1 or more clinical risk factors are present. In addition, inherited thrombophilic disorders contribute to the development of pediatric VTE. In this review, the role of inherited thrombophilic disorders in the development of pediatric VTE, as well as the benefits and limitations of thrombophilia testing, will be discussed.
小儿静脉血栓栓塞性疾病（VTE）的病因是多因素的，大多数儿童存在 1 种或多种临床危险因素。此外，遗传性血栓形成倾向也会导致小儿 VTE 的发生。在本篇综述中，将讨论遗传性血栓形成倾向在小儿 VTE 发病中的作用，以及血栓形成倾向检测的益处和局限性。
