Gerstl N, Youssef C, Cardona F, Klebermass-Schrehof K, Grill A, Weninger M, Berger A, Olischar M
Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Vienna, Austria.
Klin Padiatr. 2015 Jan;227(1):10-4. doi: 10.1055/s-0034-1377036. Epub 2015 Jan 7.
Therapeutic hypothermia (HT) has been shown to reduce the risk of death or disability and increase the rate of survival free of -disability at 18-24 months of age in hypoxic-ischemic encephalopathy (HIE).
The aim of this study was to take a national survey which (a) evaluated the practice of therapeutic HT for perinatal asphyxia in Austria, (b) evaluated the current clinical management of neonatal HIE and (c) evaluated the need for a national perinatal asphyxia and HT registry.
In January 2013, a questionnaire was sent out to the clinical heads of all neonatal level-II and level-III units in Austria.
We received replies from all 30 level II and level III units in Austria (response rate 100%). 19 units (63%) answered that they applied HT, 11 units (37%) said they transferred patients for cooling to other units, 3 of those 11 units (27%) said they applied cooling during transport. 25 units (83%) felt the necessity to establish a national registry.
The results of this survey show that there is already a high implementation of therapeutic HT in Austria, but there remains a need for information, awareness and training. Problem areas tend to be in the transport of asphyxiated neonates, brain monitoring during cooling and follow-up of affected patients. We believe, that the establishment of national guidelines and a national register could increase awareness for the importance of therapeutic HT in neonatal HIE, thus improve the Austrian management of those infants.
治疗性低温（HT）已被证明可降低缺氧缺血性脑病（HIE）患儿在18至24个月时的死亡或残疾风险，并提高无残疾生存率。
本研究旨在进行一项全国性调查，（a）评估奥地利围产期窒息治疗性HT的应用情况，（b）评估新生儿HIE的当前临床管理情况，（c）评估建立全国围产期窒息和HT登记处的必要性。
2013年1月，向奥地利所有二级和三级新生儿病房的临床负责人发送了一份问卷。
我们收到了奥地利所有30个二级和三级病房的回复（回复率100%）。19个病房（63%）回答他们应用了HT，11个病房（37%）表示他们将患者转至其他病房进行降温，这11个病房中有3个（27%）表示他们在转运过程中进行了降温。25个病房（83%）认为有必要建立一个全国登记处。
本次调查结果表明，奥地利治疗性HT的应用率已经很高，但仍需要信息、意识和培训。问题领域往往在于窒息新生儿的转运、降温期间的脑监测以及受影响患者的随访。我们认为，制定国家指南和建立全国登记处可以提高对治疗性HT在新生儿HIE中重要性的认识，从而改善奥地利对这些婴儿的管理。
