Ueno E, Isobe Y, Imazato M, Yamada A, Niimi A, Takeuchi T, Yoshii K, Imaizumi T, Akimoto S, Hanyu F
Nihon Shokakibyo Gakkai Zasshi. 1989 Oct;86(10):2434-43.
Seventeen cases with a total of eighteen insulinomas were examined by ultrasonography (US), computed tomography (CT), angiography, percutaneous transhepatic portal and pancreatic venous sampling (PTPS) and intraoperative ultrasonography (IOUS). We discussed about diagnostic accuracy of insulinomas on these diagnostic modalities. Tumor localization was achieved by US in 39%, CT in 72% and angiography in 81%. Although total 15 tumors (83%) can be correctly detected, multiple lesions were not completely ruled out. We recommended the criteria in PTPS as follows: Insulin concentration level above 200 mu U/ml. Or, both of insulin concentration ratio (step-up site/control) above three and elevation of the CPR concentration level on the PTPS. According to these criteria, the accuracy rate was 91%. Overall preoperative diagnostic accuracy was 100%. IOUS allowed us to detect the localization of the tumors completely.
对17例共18个胰岛素瘤患者进行了超声检查(US)、计算机断层扫描(CT)、血管造影、经皮经肝门静脉和胰腺静脉采血(PTPS)及术中超声检查(IOUS)。我们探讨了这些诊断方法对胰岛素瘤的诊断准确性。US对肿瘤定位的准确率为39%,CT为72%,血管造影为81%。虽然总共15个肿瘤(83%)能被正确检测到,但未完全排除多发病变。我们推荐PTPS的标准如下:胰岛素浓度水平高于200 μU/ml。或者,胰岛素浓度比(升高部位/对照)高于3且PTPS时CPR浓度水平升高。根据这些标准,准确率为91%。总体术前诊断准确率为100%。IOUS能使我们完全检测到肿瘤的定位。