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Cholangiocarcinoma in two siblings with emphysema and alpha-1-antitrypsin deficiency.

作者信息

Parham D M, Paterson J R, Gunn A, Guthrie W

机构信息

Department of Pathology, Ninewells Hospital and Medical School, Dundee.

出版信息

Q J Med. 1989 Apr;71(264):359-67.

PMID:2556731
Abstract

Two siblings with homozygous ZZ alpha-1-antitrypsin deficiency were discovered to have primary liver tumours (both cholangiocarcinomas). This lends support to the view that alpha-1-antitrypsin deficiency plays a role in the development of some primary liver tumours.

摘要

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