Suppr超能文献

腹泻和体重减轻的一种罕见但可能致命的病因:肠病相关T细胞淋巴瘤。

A rare but potentially fatal cause of diarrhoea and weight loss: enteropathy-associated T-cell lymphoma.

作者信息

Wali Gorav Neel, Tyrrell Helen Elizabeth Jane, Collins Graham P, Eagleton Helen J

机构信息

Department of Haematology, Stoke Mandeville Hospital, Aylesbury, UK.

Department of Haematology, Churchill Hospital, Oxford, UK.

出版信息

BMJ Case Rep. 2015 Jan 7;2015:bcr2014204125. doi: 10.1136/bcr-2014-204125.

Abstract

Enteropathy-associated T-cell lymphoma (EATL) is a rare but potentially fatal cause of diarrhoea and weight loss. EATL commonly presents with abdominal pain, diarrhoea and weight loss, but can also present with complications such as bowel obstruction and perforation. It is a tumour of intraepithelial lymphocytes that occurs in a relatively young population. It is the most common neoplastic complication of coeliac disease, but can occur with no prior diagnosis of coeliac disease. This case demonstrates the difficulties that can be faced in diagnosing this disorder, particularly when there is no preceding history of coeliac disease. Early diagnosis is of utmost importance in order to start treatment before the effects of malnutrition increase the risk of complications from chemotherapy. Hence awareness of the condition among general medical physicians, to whom it will often present first, is essential. However, even with prompt diagnosis, outcomes for this condition remain poor.

摘要

肠病相关T细胞淋巴瘤(EATL)是导致腹泻和体重减轻的一种罕见但可能致命的病因。EATL通常表现为腹痛、腹泻和体重减轻,但也可能出现肠梗阻和穿孔等并发症。它是一种发生在相对年轻人群中的上皮内淋巴细胞肿瘤。它是乳糜泻最常见的肿瘤性并发症,但也可能在没有先前乳糜泻诊断的情况下发生。本病例展示了诊断这种疾病时可能面临的困难,尤其是在没有乳糜泻既往病史的情况下。早期诊断至关重要,以便在营养不良的影响增加化疗并发症风险之前开始治疗。因此,普通内科医生对这种疾病的认识至关重要,因为它常常首先出现在他们面前。然而,即使及时诊断,这种疾病的预后仍然很差。

相似文献

5
Enteropathy-associated T-cell lymphoma.肠病相关 T 细胞淋巴瘤。
Crit Rev Oncol Hematol. 2011 Jul;79(1):84-90. doi: 10.1016/j.critrevonc.2010.06.006. Epub 2010 Jul 23.
7
Acute abdominal perforation as a clinical presentation of coeliac disease.以急性腹部穿孔为表现的腹腔疾病。
Arab J Gastroenterol. 2024 Feb;25(1):64-66. doi: 10.1016/j.ajg.2023.10.003. Epub 2023 Nov 21.

本文引用的文献

4
Enteropathy-associated T-cell lymphoma.肠病相关 T 细胞淋巴瘤。
Crit Rev Oncol Hematol. 2011 Jul;79(1):84-90. doi: 10.1016/j.critrevonc.2010.06.006. Epub 2010 Jul 23.
5
Enteropathy associated T-cell lymphoma and its precursor lesions.肠病相关 T 细胞淋巴瘤及其前驱病变。
Best Pract Res Clin Gastroenterol. 2010 Feb;24(1):43-56. doi: 10.1016/j.bpg.2009.11.002.
8
Celiac disease.乳糜泻
N Engl J Med. 2007 Oct 25;357(17):1731-43. doi: 10.1056/NEJMra071600.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验