Machain-Williams Carlos, Dzul-Rosado Alma R, Yeh-Gorocica Aarón B, Rodriguez-Ruz Katia G, Noh-Pech Henry, Talavera-Aguilar Lourdes, Salazar Ma Isabel, Castro-Mussot María Eugenia, Reyes-Solis Guadalupe, Garcia-Rejon Julián E, Puerto-Manzano Fernando I, Blitvich Bradley J
Laboratorio de Arbovirología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán , México.
Private Practice , Mérida, Yucatán, México.
Infect Dis Rep. 2014 Dec 9;6(4):5627. doi: 10.4081/idr.2014.5627. eCollection 2014 Nov 19.
We report a case of hand, foot and mouth disease (HFMD) in a 5-year-old male from Merida City in the Yucatan Peninsula of Mexico. A clinical and physical examination revealed that the patient had symptoms typical of HFMD, including fever, fatigue, odynophagia, throat edema, hyperemia, lesions on the hands and feet, and blisters in the oral cavity. The patient fully recovered after a convalescence period of almost three weeks. Reverse transcription-polymerase chain reaction and nucleotide sequencing revealed that the etiological agent was enterovirus 71 (EV71). The sequence has greatest (90.4%) nucleotide identity to the corresponding regions of EV71 isolates from the Netherlands and Singapore. Although HFMD is presumably common in Mexico, surprisingly there are no data in the PubMed database to support this. This case report provides the first peer-reviewed evidence of HFMD in Mexico.
我们报告了一例来自墨西哥尤卡坦半岛梅里达市的5岁男性手足口病（HFMD）病例。临床和体格检查发现，该患者具有手足口病的典型症状，包括发热、乏力、吞咽疼痛、咽喉水肿、充血、手脚部皮疹以及口腔水疱。经过近三周的恢复期，患者完全康复。逆转录聚合酶链反应和核苷酸测序显示，病原体为肠道病毒71型（EV71）。该序列与来自荷兰和新加坡的EV71分离株相应区域的核苷酸同一性最高（90.4%）。尽管手足口病在墨西哥可能很常见，但令人惊讶的是，PubMed数据库中没有数据支持这一点。本病例报告提供了墨西哥手足口病的首个经同行评审的证据。
