Malaguarnera Giulia, Bertino Gaetano, Vacante Marco, Malaguarnera Michele
1 International PhD programme in Neuropharmacology, 2 Department of Medical and Pediatric Sciences, 3 Research Center "The Great Senescence", University of Catania, Catania, Italy.
Hepatobiliary Surg Nutr. 2014 Dec;3(6):407-9. doi: 10.3978/j.issn.2304-3881.2014.07.04.
Recently, Kamiyama et al. performed N-glycan profile in hepatocellular carcinoma (HCC) using the quantitative N-glycomics procedure by way of glycoblotting technology and using an automated glycan purification system. The study showed significant differences of N-glycans profile between healthy volunteers and liver cancer patients. The glycomic approach showed us the usefulness of new tools for identification and application of a new biomarkers for cancer diagnosis and treatment. These findings reveal a new field for future markers discovery.
最近,神山等人通过糖印迹技术并使用自动聚糖纯化系统,采用定量N-糖组学方法对肝细胞癌(HCC)进行了N-聚糖分析。该研究表明,健康志愿者和肝癌患者之间的N-聚糖谱存在显著差异。糖组学方法向我们展示了新工具在癌症诊断和治疗新生物标志物识别与应用方面的有用性。这些发现揭示了未来标志物发现的一个新领域。