Role of Mg in the activation of Na-H exchange in dog red cells.
作者信息
Parker J C, Gitelman H J, McManus T J
机构信息
Department of Medicine, University of North Carolina, Chapel Hill 27599.
出版信息
Am J Physiol. 1989 Nov;257(5 Pt 1):C1038-41. doi: 10.1152/ajpcell.1989.257.5.C1038.
Abstract
Depleting dog red cells of Mg prevents activation of Na-H exchange by cell shrinkage but has no effect on activation by acidification of the cytosol. Replacing cell Mg restores the activation of Na-H exchange by cell shrinking. We conclude that Mg is required, not for the transport process per se, but for the transduction of the volume stimulus.
摘要
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