Wadiche Jacques I, Overstreet-Wadiche Linda
Department of Neurobiology, McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Department of Neurobiology, McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Neuron. 2015 Jan 7;85(1):3-5. doi: 10.1016/j.neuron.2014.12.047.
GABAergic interneurons enforce highly sparse activity patterns in principal neurons of the dentate gyrus. In this issue of Neuron, Temprana et al. (2015) show that immature adult-born neurons largely function independently of inhibitory feedback circuits, neither receiving nor generating feedback inhibition.
γ-氨基丁酸能中间神经元在齿状回的主要神经元中维持高度稀疏的活动模式。在本期《神经元》杂志中，Temprana等人（2015年）表明，未成熟的成年新生神经元在很大程度上独立于抑制性反馈回路发挥作用，既不接受也不产生反馈抑制。
