尼日利亚西南部的布鲁里溃疡：在贝宁接受治疗患者的回顾性队列研究
Buruli ulcer in South Western Nigeria: a retrospective cohort study of patients treated in Benin.
作者信息
Marion Estelle, Carolan Kevin, Adeye Ambroise, Kempf Marie, Chauty Annick, Marsollier Laurent
机构信息
Centre de Diagnostic et de Traitement de l'Ulcère de Buruli de Pobè, Fondation Raoul Follereau, Pobè, Bénin; ATOMycA, Inserm Atip-Avenir Team, CRCNA, Inserm U892, 6299 CNRS, University and Centre Hospitalier Universitaire d'Angers, Angers, France.
UMR Mivegec, IRD-CNRS-Universities of Montpellier I and II, Montpellier, Centre IRD de Montpellier, Montpellier, France.
出版信息
PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3443. doi: 10.1371/journal.pntd.0003443. eCollection 2015 Jan.
Nigeria is known to be endemic to Buruli ulcer, but epidemiological data are remarkably rare. Here, we present a large cohort of 127 PCR-confirmed M. ulcerans infection patients coming from Nigeria and treated in a neighbouring country, Benin. Severe lesions and delay of consultation are factors that should encourage establishment of a treatment centre in South Western Nigeria.
已知布氏溃疡在尼日利亚为地方病，但流行病学数据极为罕见。在此，我们展示了来自尼日利亚并在邻国贝宁接受治疗的127例经聚合酶链反应确诊的溃疡分枝杆菌感染患者的大型队列。严重病变和就诊延迟是应促使在尼日利亚西南部建立治疗中心的因素。
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