Hill Douglas A, Anderson Lindsey E, Hill Casey J, Grover William H
Annu Int Conf IEEE Eng Med Biol Soc. 2014;2014:786-8. doi: 10.1109/EMBC.2014.6943708.
Microfluidic diagnostics for use in the developing world face a number of unique challenges. Doctors and nurses in developing countries are best suited to addresses these challenges, but they lack the resources and training needed to develop their own microfluidic diagnostics. To address this need, we are developing a system of Multifluidic Evolutionary Components or MECs, "building blocks" that can be snapped together by healthcare providers in resource-limited settings to build custom diagnostic instruments. MECs operate on multiple scales of fluid volumes (from nanoliters to milliliters) and include not only fluidic but also optical, mechanical, and electronic functions. In this work we share several prototype MECs and use them to build a demonstration instrument capable of measuring the pH of a sample.
用于发展中世界的微流体诊断面临着许多独特的挑战。发展中国家的医生和护士最适合应对这些挑战，但他们缺乏开发自己的微流体诊断所需的资源和培训。为满足这一需求，我们正在开发一种多流体进化组件（MEC）系统，即“积木块”，资源有限环境中的医疗服务提供者可以将它们拼接在一起，以构建定制诊断仪器。MEC在多种流体体积尺度（从纳升到毫升）上运行，不仅包括流体功能，还包括光学、机械和电子功能。在这项工作中，我们分享了几个MEC原型，并使用它们构建了一台能够测量样品pH值的演示仪器。
