de Leon-Lomeli R, Murguia J S, Chouvarda I, Mendez M O, Gonzalez-Galvan E, Alba A, Milioli G, Grassi A, Terzano M G, Parrino L
Annu Int Conf IEEE Eng Med Biol Soc. 2014;2014:2249-52. doi: 10.1109/EMBC.2014.6944067.
Insomnia is a condition that affects the nervous and muscular system. Thirty percent of the population between 18 and 60 years suffers from insomnia. The effects of this disorder involve problems such as poor school or job performance and traffic accidents. In addition, patients with insomnia present changes in the cardiac function during sleep. Furthermore, the structure of electroencephalographic A-phases, which builds up the Cyclic Alternating Pattern during sleep, is related to the insomnia events. Therefore, the relationship between these brain activations (A-phases) and the autonomic nervous system would be of interest, revealing the interplay of central and autonomic activity during insomnia. With this goal, a study of the relationship between A-phases and heart rate fluctuations is presented. Polysomnography recording of five healthy subjects, five sleep misperception patients and five patients with psychophysiological insomnia were used in the study. Detrended Fluctuation Analysis (DFA) was used in order to evaluate the heart rate dynamics and this was correlated with the number of A-phases. The results suggest that pathological patients present changes in the dynamics of the heart rate. This is reflected in the modification of A-phases dynamics, which seems to modify of heart rate dynamics.
失眠是一种影响神经和肌肉系统的病症。18至60岁的人群中有30%患有失眠症。这种病症的影响包括学习或工作表现不佳以及交通事故等问题。此外，失眠患者在睡眠期间心脏功能会出现变化。此外，脑电图A期的结构在睡眠期间构成了周期性交替模式，它与失眠事件有关。因此，这些大脑激活（A期）与自主神经系统之间的关系将是令人感兴趣的，这揭示了失眠期间中枢和自主活动的相互作用。出于这个目的，本文呈现了一项关于A期与心率波动之间关系的研究。该研究使用了对五名健康受试者、五名睡眠感知错误患者和五名心理生理性失眠患者的多导睡眠图记录。为了评估心率动态，使用了去趋势波动分析（DFA），并将其与A期的数量相关联。结果表明，患病患者的心率动态存在变化。这反映在A期动态的改变上，而A期动态的改变似乎又改变了心率动态。
