Robustness of time frequency distribution based features for automated neonatal EEG seizure detection.

In this paper we examined the robustness of a feature-set based on time-frequency distributions (TFDs) for neonatal EEG seizure detection. This feature-set was originally proposed in literature for neonatal seizure detection using a support vector machine (SVM). We tested the performance of this feature-set with a smoothed Wigner-Ville distribution and modified B distribution as the underlying TFDs. The seizure detection system using time-frequency signal and image processing features from the TFD of the EEG signal using modified B distribution was able to achieve a median receiver operator characteristic area of 0.96 (IQR 0.91-0.98) tested on a large clinical dataset of 826 h of EEG data from 18 full-term newborns with 1389 seizures. The mean AUC was 0.93.