Kamala C S, Rao M V, George S, Prasanna N Y
Indian Pediatr. 1989 May;26(5):445-52.
One hundred and fifty cases of Japanese encephalitis (JE) in children below 12 years of age admitted to the Headquarters Hospital, Bellary Medical College during October, 1986 to January, 1987 were studied. The youngest child affected was 1 year old. The ratio of male to female was 2:1. Hindu patients (93.33%) were significantly more than Muslim patients (6.6%). The average duration of illness prior to hospitalisation was 4.2 days (SD +/- 1.9 days). Fever, headache and/or vomiting were common presenting symptoms at the onset of illness. Onset of illness was acute or sub-acute in 105 cases (70%). CSF examination showed pleocytosis with lymphocytic reaction and normal sugar. Japanese encephalitis virus was isolated from the brain biopsy tissue in one case and the seropositivity rate for JE was 50%. The mortality was 26% and was directly related to younger age, longer duration of illness prior to admission and deeper grade of coma at the time of admission. Moderate to severe sequalae were seen in 31 patients (28.82%). The mean duration of hospital stay was 8 days.
对1986年10月至1987年1月期间收治于贝拉里医学院总部医院的150例12岁以下儿童日本脑炎（乙脑）病例进行了研究。最小的患病儿童为1岁。男女比例为2:1。印度教患者（93.33%）显著多于穆斯林患者（6.6%）。住院前的平均病程为4.2天（标准差±1.9天）。发热、头痛和/或呕吐是疾病发作时常见的症状。105例（70%）病例的发病为急性或亚急性。脑脊液检查显示细胞增多伴有淋巴细胞反应且糖含量正常。1例从脑活检组织中分离出乙脑病毒，乙脑血清阳性率为50%。死亡率为26%，且与年龄较小、入院前病程较长以及入院时昏迷程度较深直接相关。31例患者（28.82%）出现中度至重度后遗症。平均住院时间为8天。
