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在MitraClip时代的二尖瓣边缘对边缘手术修复:如果遗漏了瓣环成形环会怎样?

Edge-to-edge surgical mitral valve repair in the era of MitraClip: what if the annuloplasty ring is missed?

作者信息

De Bonis Michele, Lapenna Elisabetta, Pozzoli Alberto, Giacomini Andrea, Alfieri Ottavio

机构信息

Department of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.

出版信息

Curr Opin Cardiol. 2015 Mar;30(2):155-160. doi: 10.1097/HCO.0000000000000148.

Abstract

PURPOSE OF REVIEW

The purpose of this review is to define the role of annuloplasty in the surgical edge-to-edge repair, an issue that seems particularly relevant in the current MitraClip era, when more than 15 000 patients have been submitted to a percutaneous transcatheter edge-to-edge repair without concomitant annuloplasty.

RECENT FINDINGS

Only a few studies have reported the clinical and echocardiographic outcomes of the ringless edge-to-edge mitral repair. In all of them, however, only mid-term data were provided. Recently, the long-term results of the surgical edge-to-edge procedure performed without a concomitant annuloplasty in a selected group of patients with degenerative mitral regurgitation have been published.

SUMMARY

The surgical edge-to-edge technique should always be combined with prosthetic ring annuloplasty in order to provide excellent long-term outcomes in patients with degenerative mitral regurgitation. The overall long-term results of the surgical edge-to-edge technique without annuloplasty are not satisfactory. The ringless edge-to-edge technique is not effective in the challenging setting of extensively calcified annulus. In patients without annular calcification, in whom annuloplasty was intentionally avoided, the ringless edge-to-edge repair provides acceptable results in the mid term but is associated with a high failure rate in the long term. In the MitraClip perspective, these findings emphasize the need for a reliable annuloplasty to improve the long-term outcomes of the currently available transcatheter edge-to-edge procedure.

摘要

综述目的

本综述旨在明确瓣环成形术在外科缘对缘修复中的作用,在当前MitraClip时代,这一问题似乎尤为重要,此时已有超过15000例患者接受了经皮导管缘对缘修复,且未同时进行瓣环成形术。

最新发现

仅有少数研究报告了无环缘对缘二尖瓣修复的临床和超声心动图结果。然而,所有这些研究仅提供了中期数据。最近,一组患有退行性二尖瓣反流的患者在未同时进行瓣环成形术的情况下接受外科缘对缘手术的长期结果已发表。

总结

外科缘对缘技术应始终与人工瓣环成形术相结合,以便为患有退行性二尖瓣反流的患者提供出色的长期疗效。未进行瓣环成形术的外科缘对缘技术的总体长期结果并不令人满意。无环缘对缘技术在瓣环广泛钙化这一具有挑战性的情况下无效。在故意避免进行瓣环成形术的无瓣环钙化患者中,无环缘对缘修复在中期可提供可接受的结果,但长期失败率较高。从MitraClip的角度来看,这些发现强调了需要可靠的瓣环成形术来改善当前可用的经皮导管缘对缘手术的长期疗效。

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