Foti F, Menghini D, Petrosini L, Vicari S, Valerio G, Orlandi E, Crinò A, Spera S, De Bartolo P, Mandolesi L
Department of Psychology, University "Sapienza", Via dei Marsi 78, 00185 Rome, Italy; IRCCS Santa Lucia Foundation (CERC), Via del Fosso di Fiorano 65, 00143 Rome, Italy.
Child Neuropsychiatry Unit, "Children's Hospital Bambino Gesù", Piazza Sant'Onofrio 4, 00165 Rome, Italy.
Res Dev Disabil. 2015 Mar;38:97-107. doi: 10.1016/j.ridd.2014.11.022. Epub 2015 Jan 6.
This study was aimed at evaluating the spatial abilities in individuals with Prader-Willi syndrome (PWS) by using an ecological large-scale task with multiple rewards. To evaluate the extent of spatial deficit in PWS individuals, we compare their performances with those of individuals with Williams Syndrome (WS) in which the spatial deficits have been widely described. Participants had to explore an open space to search nine rewards placed in buckets arranged according to three spatial configurations: a Cross, a 3×3 Matrix and a Cluster composed by three groups of three buckets each. PWS individuals exhibited an explorative deficit in Cluster and Cross configurations, while WS participants in Matrix and Cross configurations. The findings indicate that the structural affordances of the environment influence the explorative strategies and can be related to how spatial information is processed.
本研究旨在通过使用一项具有多重奖励的生态大规模任务，评估普拉德-威利综合征（PWS）患者的空间能力。为了评估PWS患者空间缺陷的程度，我们将他们的表现与威廉姆斯综合征（WS）患者的表现进行了比较，在WS患者中，空间缺陷已被广泛描述。参与者必须探索一个开放空间，以寻找放置在根据三种空间配置排列的桶中的九个奖励：一个十字形、一个3×3矩阵和一个由三组每组三个桶组成的集群。PWS患者在集群和十字形配置中表现出探索缺陷，而WS参与者在矩阵和十字形配置中表现出探索缺陷。研究结果表明，环境的结构可供性会影响探索策略，并且可能与空间信息的处理方式有关。
