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使用EBT3型放射变色薄膜对50 kV放疗设备进行质量保证:一项可行性研究。

Quality Assurance of a 50-kV Radiotherapy Unit Using EBT3 GafChromic Film: A Feasibility Study.

作者信息

Steenbeke Femke, Gevaert Thierry, Tournel Koen, Engels Benedikt, Verellen Dirk, Storme Guy, De Ridder Mark

机构信息

Department of Radiotherapy, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

Department of Radiotherapy, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium

出版信息

Technol Cancer Res Treat. 2016 Feb;15(1):163-70. doi: 10.1177/1533034614565910. Epub 2015 Jan 9.

Abstract

PURPOSE

Radiochromic EBT3 film is gaining acceptance as a valuable dosimetry system for high-energy photon beams. The advantages of these films over other dosimetry systems are low spectral sensitivity and high spatial resolution. The aim of this study was to validate EBT3 film as a dosimeter for machine and treatment quality assurance (QA) of a 50-kV radiotherapy unit.

METHODS AND MATERIALS

Absolute and relative doses were acquired using EBT3 GafChromic films and compared to a parallel-plate ionization chamber (IC), the standard IC for low-energy X-rays. EBT3 was also used to evaluate beam profiles and output factors. Two films above each other, mimicking the clinical situation of a dosimeter on top of the skin, were simultaneously irradiated to evaluate EBT3 as in vivo dosimeter. All films were irradiated for 3 minutes, which corresponds with a surface dose of 3.25 ± 0.07 Gy.

RESULTS

A fifth-order polynomial function was found to be the best fit for the calibration curves. Good agreement between IC and EBT3 was found for absolute (0.92% for green and red color channels) and relative (1.2% and 1.0% for green and red color channels, respectively) dosimetry. Output factors for IC and EBT3 were comparable within 2.04% and 1.02% for the green and red color channels, respectively. Flatness and symmetry at the surface were within 2%. By applying film as in vivo dosimeter, an absorption of 4.70% needs to be taken into account with respect to the surface dose.

CONCLUSION

EBT3 GafChromic film is a feasible and valuable QA and dosimetry tool for a 50-kV radiotherapy unit. EBT3 can be used for absolute and relative dosimetry, measurement of output factors and beam profiles. In vivo patient-specific QA can also be performed if one corrects for the dose absorption of the film.

摘要

目的

放射变色EBT3薄膜作为一种用于高能光子束的有价值的剂量测定系统正逐渐得到认可。这些薄膜相对于其他剂量测定系统的优点是光谱灵敏度低和空间分辨率高。本研究的目的是验证EBT3薄膜作为50 kV放射治疗单元的机器和治疗质量保证(QA)剂量计的有效性。

方法和材料

使用EBT3 GafChromic薄膜获取绝对剂量和相对剂量,并与平行板电离室(IC)(低能X射线的标准IC)进行比较。EBT3还用于评估射野轮廓和输出因子。将两片薄膜叠放在一起,模拟剂量计置于皮肤上方的临床情况,同时进行照射,以评估EBT3作为体内剂量计的情况。所有薄膜均照射3分钟,这对应于3.25±0.07 Gy的表面剂量。

结果

发现五阶多项式函数最适合校准曲线。在绝对剂量测定(绿色通道和红色通道分别为0.92%)和相对剂量测定(绿色通道和红色通道分别为1.2%和1.0%)方面,IC和EBT3之间具有良好的一致性。IC和EBT3的输出因子在绿色通道和红色通道中分别在2.04%和1.02%以内具有可比性。表面的平坦度和对称性在2%以内。通过将薄膜用作体内剂量计,相对于表面剂量,需要考虑4.70%的吸收。

结论

EBT3 GafChromic薄膜是一种用于50 kV放射治疗单元的可行且有价值的质量保证和剂量测定工具。EBT3可用于绝对和相对剂量测定、输出因子和射野轮廓的测量。如果对薄膜的剂量吸收进行校正,也可以进行针对患者个体的体内质量保证。

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