Borges Alessandra Bühler, Batista Graziela Ribeiro, Arantes Paula Tamião, Wiegand Annette, Attin Thomas, Torres Carlos Rocha Gomes
Assistant Professor, Department of Restorative Dentistry, School of Dentistry UNESP, São Jose dos Campus, São Paulo, Brazil, e-mail:
PhD Student, Department of Restorative Dentistry, School of Dentistry UNESP, São Jose dos Campus, São Paulo, Brazil.
J Contemp Dent Pract. 2014 Jul 1;15(4):407-12. doi: 10.5005/jp-journals-10024-1553.
The aim of this study was to investigate the Influence of simulated pulpal pressure on efficacy of bleaching gels.
Cylindrical enamel-dentin specimens from bovine teeth (3 mm diameter, enamel and dentin layer each 1 mm thick) were divided into 4 groups, according to the bleaching treatment: negative control (non-bleached), bleached with 10% carbamide peroxide (CP), bleached with 7.5% hydrogen peroxide (HP) and bleached with 35% hydrogen peroxide. Ten percent CP gel was applied for 8 h/day and 7.5% HP for 1 h/day, during 14 days. For 35% HP treatment, two sessions of 45 minutes each were employed. In intermediate periods specimens were stored in artificial saliva. Experimental groups (n = 19) were subdivided according to the simulation of pulpal pressure (25 mm Hg) during bleaching treatment. Initial color measurement and after bleaching treatment were assessed by spectrophotometry, using CIE Lab* system. The data were statistically analyzed by ANOVA and Dunnett's post-hoc tests (p < 0.05).
There was significant difference of ΔE for all experimental groups compared to negative control group, according to Dunnett's test (p < 0.0001). There were no significant difference for total color variation (ΔE) among experimental groups (p > 0.05).
It was concluded that all bleaching gels showed bleaching efficacy compared to non-bleached group and that the simulated pulpal pressure did not Influence the bleaching outcomes of the tested gels.
Although numerous in vitro studies investigating the efficacy of bleaching agents have been performed, they do not properly simulate the pulpal pressure. In order to make these studies closer to clinical conditions, it is important to reproduce these conditions in laboratory, so the results can be more reliable. This in vitro study was performed under simulated pulpal pressure, aiming to investigate its Influence on dental bleaching outcomes.
本研究旨在探讨模拟牙髓压力对漂白凝胶疗效的影响。
将牛牙的圆柱形釉质-牙本质标本（直径3毫米，釉质和牙本质层各厚1毫米）根据漂白处理分为4组：阴性对照组（未漂白）、用10%过氧化脲（CP）漂白、用7.5%过氧化氢（HP）漂白和用35%过氧化氢漂白。10% CP凝胶每天使用8小时，7.5% HP凝胶每天使用1小时，持续14天。对于35% HP处理，采用两个45分钟的疗程。在中间阶段，标本保存在人工唾液中。实验组（n = 19）根据漂白处理期间模拟的牙髓压力（25毫米汞柱）进一步细分。使用CIE Lab*系统通过分光光度法评估初始颜色测量和漂白处理后的颜色。数据通过方差分析和Dunnett事后检验进行统计学分析（p < 0.05）。
根据Dunnett检验，与阴性对照组相比，所有实验组的ΔE均有显著差异（p < 0.0001）。实验组之间的总颜色变化（ΔE）无显著差异（p > 0.05）。
得出的结论是，与未漂白组相比，所有漂白凝胶均显示出漂白效果，并且模拟的牙髓压力不影响测试凝胶的漂白结果。
尽管已经进行了大量研究漂白剂疗效的体外研究，但它们并未恰当地模拟牙髓压力。为了使这些研究更接近临床情况，在实验室中重现这些条件很重要，这样结果才能更可靠。本体外研究在模拟牙髓压力下进行，旨在研究其对牙齿漂白结果的影响。
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