Watson Ian T, Murzaku Era
Texas A&M College of MedicineBryanTexas.
Department of Dermatology, University of Texas Southwestern Medical CenterDallasTexas.
Proc (Bayl Univ Med Cent). 2019 Jan 15;32(1):88-89. doi: 10.1080/08998280.2018.1523643. eCollection 2019 Jan.
We present the case of a 55-year-old black man with coccidiomycosis presenting as a cutaneous plaque on the upper lip. Coccidiomycosis, or "valley fever," is caused by the virulent, dimorphic, soil-dwelling fungus . Seen in up to 50% of symptomatic patients, skin involvement by coccidiomycosis can present as papules, pustules, plaques, nodules, abscesses, or ulcerations. Diagnosis of coccidiomycosis relies on serology and identification in clinical specimens, and first-line treatment includes fluconazole, ketoconazole, or itraconazole. Recognizing the cutaneous manifestations of this mycotic infection is essential for diagnosis in otherwise asymptomatic patients.
我们报告一例55岁黑人男性球孢子菌病患者,其表现为上唇皮肤斑块。球孢子菌病,即“山谷热”,由一种毒性强的、双相的、生长于土壤中的真菌引起。在多达50%的有症状患者中可见,球孢子菌病累及皮肤时可表现为丘疹、脓疱、斑块、结节、脓肿或溃疡。球孢子菌病的诊断依赖血清学检查及临床标本鉴定,一线治疗包括氟康唑、酮康唑或伊曲康唑。认识这种真菌感染的皮肤表现对于诊断无症状患者至关重要。