Elgart George W
Department of Dermatology, University of Miami Miller School of Medicine, FL, USA.
Semin Cutan Med Surg. 2014 Sep;33(3):146-50. doi: 10.12788/j.sder.0112.
Fungal infection is a common clinical problem in dermatology. While most cases in practice are superficial infections, invasive subcutaneous mycoses are important to recognize and treat, as these conditions often have significant morbidity and mortality. Deep fungi demonstrate species-specific syndromes and may be identified by clinical and histological features in addition to serological evaluation and culture. Identification of the common innoculation subcutaneous mycoses, as well as those associated with pulmonary primary infection and dissemination to the skin is important, as treatments vary by organism and clinical setting. This overview will help to identify the key dermatological presentations of subcutaneous fungal infection, and the clues they give to cause.
真菌感染是皮肤科常见的临床问题。虽然在实际情况中大多数病例为浅表感染,但侵袭性皮下真菌病的识别和治疗很重要,因为这些病症往往具有较高的发病率和死亡率。深部真菌表现出特定菌种的综合征,除血清学评估和培养外,还可通过临床和组织学特征进行识别。识别常见的接种性皮下真菌病以及与肺部原发性感染和皮肤播散相关的真菌病很重要,因为治疗方法因病原体和临床情况而异。本综述将有助于识别皮下真菌感染的关键皮肤表现及其提示的病因线索。