Zhao Li-Lai, Tong Pei-Jian, Xiao Lu-Wei, Zhu Qiu-Liang, Xu Bin, Yan Mao-Hua
1st Department of Orthopaedics, Anji People's Hospital of Zhejiang, Chiha.
Zhongguo Gu Shang. 2014 Nov;27(11):908-11.
To compare therapeutic effects of local injection with autoallergic platelet rich plasma (PRP) or autoallergic whole blood (AWB) for the treatment of chronic tennis elbow.
From January 2011 to January 2014, 40 patients with chronic tennis elbow were divided into 2 groups, 20 cases in each group: PRP group and AWB group. There were 20 patients in PRP group treated with local injection of autoallergic platelet rich plasma, including 5 males and 15 females, with an average age of (47.50 ± 9.86) years old; and the average course of disease was (4.67 ± 3.27) months. Among the 20 patients in AWB group treated with local injection of autoallergic whole blood, 3 patients were male and 17 patients were female, with an average age of (46.50 ± 9.96) years old;and the average course of disease was (4.53 ± 2.27) months. The elbow joint was fixed with elastic stockings after injection. All the patients were guided to do strengthening and extension exercises during the follow-up period. Visual analog scale (VAS), Mayo scores for elbow and pressure pain threshold (PPT) were used to evaluate clinical effects after injection immediately and 4,8 weeks after treatment. Results:All the patients were followed up,there were no infections and swelling occurred. The VAS, Mayo and PPT scores of patients in PRP group were improved from pre-therapy 7.22 ± 1.32, 56.71 ± 10.90 and 17.47 ± 4.62 to 2.73 ± 1.00, 91.59 ± 6.95 and 21.35 ± 4.80 respectively 8 weeks after treatment. The VAS, Mayo and PPT scores of patients in AWB group were improved from pre-therapy 7.16 ±1.27, 54.72 ± 8.36 and 17.06 ± 4.83 to 3.81 ± 1.36, 82.06 ± 7.89 and 20.12 ± 4.97 respectively 8 weeks after treatment. All the pain and functional variables including VAS, PPT, and Mayo scores were improved significantly in both groups 4 weeks after injection. On the 4th week after injection, there was no statistically significant difference in PPT between two groups; while the VAS and Mayo score of AWB group were lower than those of PRP group. On the 8th week after injection, the VAS of AWB group was higher than that of PRP group; but the Mayo and PPT scores of AWB group were lower than those of PRP group.
PRP and AWB injections are both effective to treat chronic lateral epicondylitis. Compared with AWB injection, PRP injection may be more effective in releasing pain and improving function for a longer time.
比较自体富血小板血浆（PRP）局部注射与自体全血（AWB）局部注射治疗慢性网球肘的疗效。
2011年1月至2014年1月，将40例慢性网球肘患者分为2组，每组20例：PRP组和AWB组。PRP组20例患者采用自体富血小板血浆局部注射治疗，其中男5例，女15例，平均年龄（47.50±9.86）岁；平均病程（4.67±3.27）个月。AWB组20例患者采用自体全血局部注射治疗，其中男3例，女17例，平均年龄（46.50±9.96）岁；平均病程（4.53±2.27）个月。注射后用弹力绷带固定肘关节。随访期间指导所有患者进行强化和伸展锻炼。采用视觉模拟评分法（VAS）、肘关节Mayo评分和压痛阈值（PPT）评估注射后即刻、治疗后4周和8周的临床疗效。结果：所有患者均获随访，未发生感染及肿胀。PRP组患者治疗8周后VAS、Mayo和PPT评分分别从治疗前的7.22±1.32、56.71±10.90和17.47±4.62改善至2.73±1.00、91.59±6.95和21.35±4.80。AWB组患者治疗8周后VAS、Mayo和PPT评分分别从治疗前的7.16±1.27、54.72±8.36和17.06±4.83改善至3.81±1.36、82.06±7.89和20.12±4.97。两组患者注射后4周时，包括VAS、PPT和Mayo评分在内的所有疼痛和功能变量均有显著改善。注射后第4周，两组间PPT差异无统计学意义；而AWB组的VAS和Mayo评分低于PRP组。注射后第8周，AWB组的VAS高于PRP组；但AWB组的Mayo和PPT评分低于PRP组。
PRP和AWB注射治疗慢性外侧上髁炎均有效。与AWB注射相比，PRP注射在缓解疼痛和改善功能方面可能更有效，且作用时间更长。
