Averell Nicholas, Goodwin Brandon, Park Seungkyu, Spicer Seth, Wilson Margaret, Mitchell Jessica, Martinez Nichole, Palhang Meejan, Jabon Jaimy, Jermyn Richard
Department of Medicine, Rowan University School of Osteopathic Medicine, Stratford, NJ 08043, USA.
Futures Forward Research Institute, Toms River, NJ 08753, USA.
Pain Manag. 2024;14(4):223-233. doi: 10.1080/17581869.2024.2360381. Epub 2024 Jun 14.
To investigate the analyze the relationship between concentration platelet-dose in platelet-rich plasma (PRP) injections and improvements in pain when treating lateral epicondylitis. A systematic review was conducted into five medical databases, exploring the difference in pain outcomes based on concentration of PRP. Initial querying of the databases yielded 1408 articles with 20 articles ultimately included. There was no statistical significance between effect sizes of the two treatment groups (high and low platelet concentration; p = 0.976). Both large and small concentrations of platelets depict significant reduction in pain, however, between subgroups there was no significance. It can thus be concluded that concentration of platelets in PRP does not impact overall pain relief.
为了研究富血小板血浆（PRP）注射中血小板剂量浓度与治疗肱骨外上髁炎时疼痛改善之间的关系。对五个医学数据库进行了系统综述，探讨基于PRP浓度的疼痛结果差异。对数据库的初步查询产生了1408篇文章，最终纳入20篇文章。两个治疗组（高血小板浓度和低血小板浓度）的效应大小之间没有统计学意义（p = 0.976）。高浓度和低浓度的血小板均显示疼痛显著减轻，然而，亚组之间没有显著性差异。因此可以得出结论，PRP中血小板的浓度不会影响总体疼痛缓解。
