López-Caneda Eduardo, Mota Nayara, Crego Alberto, Velasquez Teresa, Corral Montserrat, Rodríguez Holguín Socorro, Cadaveira Fernando
Adicciones. 2014;26(4):334-59.
Binge drinking (BD) is the most common problematic drinking pattern during adolescence and youth. At the same time, it is a period marked by profound structural and functional brain changes, which may be affected by heavy alcohol consumption. In recent years, a considerable number of studies that attempt to characterize the effects of BD on the brain has been published. However, to date there is not any critical review in Spanish language on neurostructural, neurophysiological and cognitive consequences that may result from the maintenance of a BD pattern of alcohol consumption during adolescence and youth. The purpose of this review is to critically summarize the main research results on the effects of BD on the brain. To this end, a literature search in databases Web of Knowledge, PubMed and PsycINFO for the period 2000-2013 was performed. In general, studies agree that BD is associated with 1) lower performance on tasks assessing cognitive processes such as attention, memory and executive functions, 2) structural changes (in white matter and gray matter) in different brain regions and 3) neurophysiological abnormalities (hyper/hypoactivation) linked to different cognitive processes. These results, although still need to be contrasted, warn about important consequences that could result from the persistence of BD on a young and still maturing brain.
暴饮(BD)是青少年和青年时期最常见的问题饮酒模式。与此同时,这一时期的大脑在结构和功能上会发生深刻变化,而大量饮酒可能会对这些变化产生影响。近年来,已经发表了相当多试图描述暴饮对大脑影响的研究。然而,迄今为止,还没有用西班牙语对青少年和青年时期维持暴饮酒精消费模式可能导致的神经结构、神经生理和认知后果进行的批判性综述。本综述的目的是批判性地总结关于暴饮对大脑影响的主要研究结果。为此,我们在2000年至2013年期间对Web of Knowledge、PubMed和PsycINFO数据库进行了文献检索。总体而言,研究一致认为,暴饮与以下方面有关:1)在评估注意力、记忆和执行功能等认知过程的任务中表现较差;2)不同脑区的结构变化(白质和灰质);3)与不同认知过程相关的神经生理异常(过度/不足激活)。这些结果虽然仍需对比,但警示了暴饮持续作用于仍在发育的年轻大脑可能产生的重要后果。