Signorile Pietro G, Baldi Alfonso
Fondazione Italiana Endometriosi, Rome, Italy.
Fondazione Italiana Endometriosi, Rome, Italy; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Italy.
Int J Biochem Cell Biol. 2015 Mar;60:19-22. doi: 10.1016/j.biocel.2014.12.019. Epub 2015 Jan 9.
Endometriosis is a recurrent and benign gynecological disorder characterized by the presence of endometrial tissue outside the cavity of the uterus. It is one of the most common diseases in the gynecological field, affecting about 10% of the female population in reproductive age. Despite this, its pathogenesis is still unacknowledged, there is a lack of early diagnostic markers and current therapies are only symptomatic. Considering the relevant health problems caused by endometriosis, all new information on this disease may have important clinical implications. The aim of this article is to summarize the latest advances in the pathogenesis, diagnosis and therapy of endometriosis that have recently been proposed by our research group. The possible clinical implications of these findings will be discussed.
子宫内膜异位症是一种复发性良性妇科疾病,其特征是子宫腔外存在子宫内膜组织。它是妇科领域最常见的疾病之一,影响约10%的育龄女性。尽管如此,其发病机制仍未明确,缺乏早期诊断标志物,目前的治疗仅为对症治疗。考虑到子宫内膜异位症引起的相关健康问题,关于这种疾病的所有新信息可能都具有重要的临床意义。本文旨在总结我们研究小组最近提出的子宫内膜异位症发病机制、诊断和治疗方面的最新进展。将讨论这些发现可能的临床意义。