Bhosale Guruprasad P, Shah Veena R
Department of Anaesthesia and Critical Care, Institute of Kidney Diseases and Research Center and Institute of Transplantation Sciences, Civil Hospital Campus, Ahmedabad, Gujarat, India.
Saudi J Kidney Dis Transpl. 2015 Jan;26(1):107-10. doi: 10.4103/1319-2442.148754.
Bicarbonate dialysis is the treatment modality of choice for correction of metabolic acidosis in chronic renal failure. However, improper selection of dialysate concentrate can result in life-threatening human errors. We report a case of iatrogenic severe hypernatremia (sodium 207 mEq/L) and severe metabolic acidosis (pH 6.65) that resulted due to accidental use of inappropriate bicarbonate concentrate for hemodialysis treatment. There was successful recovery in this patient with no neurological sequelae. To the best of our knowledge, this is the first case report in adults of severe hypernatremia along with severe metabolic acidosis due to error in the preparation of dialysis fluid.
碳酸氢盐透析是纠正慢性肾衰竭代谢性酸中毒的首选治疗方式。然而,透析液浓缩液选择不当可能导致危及生命的人为错误。我们报告一例医源性严重高钠血症(血钠207 mEq/L)和严重代谢性酸中毒(pH 6.65)病例,该病例是由于在血液透析治疗中意外使用了不适当的碳酸氢盐浓缩液所致。该患者成功康复,无神经后遗症。据我们所知,这是第一例关于因透析液配制错误导致成人严重高钠血症并伴有严重代谢性酸中毒的病例报告。