di Meo Nicola, Stinco Giuseppe, Gubertini Nicoletta, Patriarca Maria Martina, Trevisan Giusto
Nicola di Meo, MD, Dermatology Department, University of Trieste , Ospedale Maggiore di Trieste, IV piano Palazzina Infettiv,i Piazza Ospedale 1, 34151 Trieste, Italy;
Acta Dermatovenerol Croat. 2014;22(4):298-300.
In recent years, group G Streptococcus has been reported with increasing frequency as the cause of a variety of human infections. Underlying host factors such as immunosuppression, malignancy, diabetes mellitus, and rheumatoid arthritis may be predisposing conditions leading to infection. Toxic involvement and post-streptococcal sequalae, once believed to be exclusive to infections caused by group A Streptococcus, are now known to occur following acute group G Streptococcus and group C Streptococcus infections. We report on a case of group G Streptococcus bacteremia and recurrent cellulitis with toxic involvement. Patient blood cultures were always negative for β-hemolytic Streptococci in all the recurrences, except during the last one. Antibiotic therapy based on antibiogram quickly resolved the infection. A regimen of intramuscular injection of 1.2 million units of benzathine penicillin every 15 days for one year prevented recurrences of cellulitis.
近年来，G 组链球菌作为多种人类感染的病因，其报告频率不断增加。免疫抑制、恶性肿瘤、糖尿病和类风湿性关节炎等潜在宿主因素可能是导致感染的易感条件。毒性累及和链球菌感染后后遗症，曾被认为是 A 组链球菌感染所特有的，现在已知在急性 G 组链球菌和 C 组链球菌感染后也会发生。我们报告一例伴有毒性累及的 G 组链球菌菌血症和复发性蜂窝织炎病例。除最后一次复发外，患者所有复发时的血培养β溶血性链球菌均为阴性。基于药敏试验的抗生素治疗迅速控制了感染。每 15 天肌肉注射 120 万单位苄星青霉素，持续一年的治疗方案预防了蜂窝织炎的复发。
