Ah基因位点：毒性、癌症、突变及出生缺陷方面的遗传差异。 - Suppr

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超能文献

The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects.

作者信息

Nebert D W

机构信息

Wesleyan University, Middletown, Connecticut.

出版信息

Crit Rev Toxicol. 1989;20(3):153-74. doi: 10.3109/10408448909017908.

DOI:10.3109/10408448909017908

PMID:2558673

Abstract

摘要

相似文献

The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects.Ah基因位点：毒性、癌症、突变及出生缺陷方面的遗传差异。

Crit Rev Toxicol. 1989;20(3):153-74. doi: 10.3109/10408448909017908.

Competitive interaction for the Ah receptor by polycyclic aromatic hydrocarbons which do not induce aryl hydrocarbon hydroxylase in C3H/10T1/2 mouse embryo fibroblasts.多环芳烃对Ah受体的竞争性相互作用，这些多环芳烃在C3H/10T1/2小鼠胚胎成纤维细胞中不诱导芳烃羟化酶。

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2,3,7,8,-Tetrachlorodibenzo-p-dioxin: segregation of toxocity with the Ah locus.2,3,7,8-四氯二苯并对二恶英：毒性与芳烃（Ah）位点的分离

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The Ah receptor and the mechanism of dioxin toxicity.芳烃受体与二噁英毒性机制

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A brief review of the Ah locus.Ah位点简述。

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Ah receptor in mice genetically "nonresponsive" for cytochrome P4501A1 induction: cytosolic Ah receptor, transformation to the nuclear binding state, and induction of aryl hydrocarbon hydroxylase by halogenated and nonhalogenated aromatic hydrocarbons in embryonic tissues and cells.对细胞色素P4501A1诱导具有基因“无反应性”的小鼠中的芳烃受体：胞质芳烃受体、向核结合状态的转变以及胚胎组织和细胞中卤代和非卤代芳烃对芳烃羟化酶的诱导。

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Distribution and excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin in congenic strains of mice which differ at the Ah locus.2,3,7,8-四氯二苯并对二恶英在Ah位点存在差异的同源近交系小鼠中的分布与排泄

Drug Metab Dispos. 1986 Jan-Feb;14(1):34-40.

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Influence of the Ah locus on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the hepatic epidermal growth factor receptor.Ah基因座对2,3,7,8-四氯二苯并对二恶英对肝表皮生长因子受体影响的作用

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The effects of TCDD on receptors for epidermal growth factor, glucocorticoid, and estrogen in Ah-responsive and -nonresponsive congenic mice and the effects of TCDD on estradiol metabolism in a liver tumor promotion model in female rats.2,3,7,8-四氯二苯并对二恶英（TCDD）对Ah反应型和非反应型近交系小鼠中表皮生长因子、糖皮质激素和雌激素受体的影响，以及TCDD对雌性大鼠肝肿瘤促进模型中雌二醇代谢的影响。

Prog Clin Biol Res. 1990;331:187-202.

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