Instituto de Bioquímica, Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal; E-Mails:
Biosensors (Basel). 2014 Feb 4;4(1):1-17. doi: 10.3390/bios4010001. eCollection 2014 Mar.
In the present study, we describe the biochemical properties and effects of nitric oxide (NO) in intact and dysfunctional arterial and venous endothelium. Application of the NO electrochemical sensor in vivo and in vitro in erythrocytes of healthy subjects and patients with vascular disease are reviewed. The electrochemical NO sensor device applied to human umbilical venous endothelial cells (HUVECs) and the description of others NO types of sensors are also mentioned.
在本研究中，我们描述了完整和功能失调的动脉和静脉内皮中一氧化氮（NO）的生化特性和作用。综述了 NO 电化学传感器在健康受试者和血管疾病患者体内和体外的红细胞中的应用。还提到了应用于人脐静脉内皮细胞（HUVEC）的电化学 NO 传感器装置和其他类型的 NO 传感器的描述。
