Sato Masayo, Vietri Jeffrey, Flynn Jennifer A, Fujiwara Saeko
Eli Lilly K.K., Lilly Research Laboratories, Kobe 651-0086, Japan.
Kantar Health, Health Outcomes Practice, Via Paleocapa 7, 20121 Milan, Italy.
J Osteoporos. 2014;2014:909153. doi: 10.1155/2014/909153. Epub 2014 Dec 23.
This study was conducted to identify characteristics associated with treatment for osteoporosis among women aged 50 years and older in Japan and to explore differences among patients according to treatment regimen. Data were provided by a large annual survey representative of Japanese aged 18 and older; all measures were by self-report. Women aged 50 and older who reported diagnosed osteoporosis (N = 900) were compared based on current treatment status using bivariate statistics and logistic regression. Approximately 1 in 3 women in this study reporting diagnosed osteoporosis were currently untreated. Factors associated with current treatment for osteoporosis included having ≥1 physician visit in the prior 6 months (OR = 5.4, P < 0.001), self-rated moderate or severe osteoporosis (OR = 2.8, P < 0.001), completion of menopause (OR = 1.6, P < 0.05), and family history of osteoporosis (OR = 1.5, P < 0.05), while longer duration of osteoporosis diagnosis (OR = 0.9, P < 0.05) and arthritis (OR = 0.7, P < 0.05) were associated with lower odds of treatment. These findings suggest that diagnosed patients are not being actively managed in the longer term, and efforts need to be made to ensure that patients stay engaged with their healthcare providers.
本研究旨在确定日本50岁及以上女性骨质疏松症治疗的相关特征,并探讨不同治疗方案患者之间的差异。数据来自一项针对18岁及以上日本人群的大型年度代表性调查;所有测量均通过自我报告进行。对报告已确诊骨质疏松症的50岁及以上女性(N = 900),根据当前治疗状况,采用双变量统计和逻辑回归进行比较。本研究中约三分之一报告已确诊骨质疏松症的女性目前未接受治疗。与当前骨质疏松症治疗相关的因素包括在过去6个月内有≥1次就诊(OR = 5.4,P < 0.001)、自我评定为中度或重度骨质疏松症(OR = 2.8,P < 0.001)、绝经结束(OR = 1.6,P < 0.05)以及骨质疏松症家族史(OR = 1.5,P < 0.05),而骨质疏松症诊断时间较长(OR = 0.9,P < 0.05)和患有关节炎(OR = 0.7,P < 0.05)与治疗几率较低相关。这些发现表明,已确诊的患者在长期内未得到积极管理,需要努力确保患者与医疗服务提供者保持联系。