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全麻下手术治疗重度化脓性汗腺炎:113 例患者 363 次原发性手术治疗的研究。

Surgery under general anaesthesia in severe hidradenitis suppurativa: a study of 363 primary operations in 113 patients.

机构信息

Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Department of Dermatology, Antonius Hospital, Sneek, The Netherlands.

出版信息

J Eur Acad Dermatol Venereol. 2015 Aug;29(8):1590-7. doi: 10.1111/jdv.12952. Epub 2015 Jan 15.

Abstract

BACKGROUND

Treatment of hidradenitis suppurativa (HS) is a difficult undertaking, especially as there is no consensus on what surgical technique is preferred. At our centre severe HS (Hurley II/III) is operated under general anaesthesia, mostly with the STEEP procedure.

OBJECTIVES

To investigate characteristics, surgical outcomes and patient satisfaction of HS patients who underwent deroofing or STEEP under general anaesthesia.

METHODS

A clinical records-based retrospective analysis was conducted of all patients who had surgery under general anaesthesia between 1999 and 2013. Patient satisfaction was retrospectively investigated with questionnaires.

RESULTS

A total of 482 operations (363 primary operations and 119 re-operations) were performed during the study period. The proportion of women in the included population was 68%. The median diagnostic delay (patient's and doctor's delay) was 6.5 years. Relapses occurred after 29.2% of primary operations. Women had higher relapse rates than men [odds ratio 2.85 (1.07;7.61)]. Hypergranulation of the wound was the most common complication and occurred in 7% of all operations. The median score patients attributed to the medical effect of surgery was eight of 10 (zero corresponding to very dissatisfied and 10 to very satisfied).

CONCLUSION

The diagnostic delay in HS is long due to a lack of knowledge in both patients and health care professionals, indicating that there is a need for education. Deroofing and the STEEP are effective surgical procedures in severe cases of HS and lead to a relatively high patient satisfaction. The postoperative relapse risk is higher in women. Prospective studies are required for the development of clear guidelines on the appropriate choice of surgery.

摘要

背景

治疗化脓性汗腺炎(HS)是一项艰巨的任务,尤其是因为对于哪种手术技术更优尚无共识。在我们中心,严重的 HS(Hurley II/III)在全身麻醉下进行手术,主要采用 STEEP 手术。

目的

调查在全身麻醉下接受去顶或 STEEP 手术的 HS 患者的特征、手术结果和患者满意度。

方法

对 1999 年至 2013 年间在全身麻醉下接受手术的所有患者进行基于临床记录的回顾性分析。通过问卷调查对患者满意度进行回顾性调查。

结果

在研究期间共进行了 482 例手术(363 例初次手术和 119 例再次手术)。纳入人群中女性占 68%。确诊延迟(患者和医生的延迟)中位数为 6.5 年。初次手术后复发率为 29.2%。女性的复发率高于男性[比值比 2.85(1.07;7.61)]。伤口过度肉芽形成是最常见的并发症,发生在所有手术的 7%。患者对手术医疗效果的评分中位数为 10 分中的 8 分(0 分对应非常不满意,10 分对应非常满意)。

结论

由于患者和医疗保健专业人员缺乏知识,HS 的诊断延迟时间较长,这表明需要进行教育。去顶和 STEEP 是严重 HS 的有效手术方法,可带来相对较高的患者满意度。女性术后复发风险较高。需要前瞻性研究来制定明确的手术选择指南。

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