Tidman Michael J
Department of Dermatology, Royal Infirmary of Edinburgh, UK.
Practitioner. 2014 Oct;258(1775):27-30, 3.
Rosacea is more common in women than men and occurs more frequently in fair-skinned individuals, usually in the middle years of life. It tends to localise to the cheeks, forehead, chin and nose, sometimes showing marked asymmetry. Only very occasionally does it involve areas other than the face. Rosacea is usually characterised by erythematous papules, pustules, and occasionally plaques (papulopustular rosacea), which fluctuate in severity, typically on a background of erythema and telangiectasia. In some individuals, facial redness can be prominent and permanent (erythematotelangiectatic rosacea). Important distinguishing features from acne are a lack of comedones, absence of involvement of extra-facial areas, and the presence of flushing. Hypertrophy of facial sebaceous glands, sometimes with fibrotic changes, may result in unsightly thickening of the skin. Men, in particular, may develop marked enlargement and distortion of the nose. Occasionally, the predominant feature of rosacea is swelling of the eyelids and firm oedematous changes elsewhere on the face. Involvement of the eyes is an important, underdiagnosed complication that may result in significant ocular morbidity. Involvement of the external eye surfaces by rosacea usually necessitates ophthalmological advice. There is often no correlation between the degree of ocular and cutaneous rosacea, and ocular rosacea may occur alone. Rosacea is a disfiguring condition that can have a major psychosocial impact, and its detrimental effect on emotional health and quality of life is often overlooked.
酒渣鼻在女性中比男性更常见,在皮肤白皙的人群中更频繁出现,通常发生在中年时期。它往往局限于脸颊、前额、下巴和鼻子,有时表现出明显的不对称。只有极少数情况下它会累及面部以外的区域。酒渣鼻通常的特征是红斑丘疹、脓疱,偶尔还有斑块(丘疹脓疱型酒渣鼻),严重程度会波动,典型情况是在红斑和毛细血管扩张的背景下出现。在一些个体中,面部发红可能很明显且持续存在(红斑毛细血管扩张型酒渣鼻)。与痤疮的重要区别特征是没有粉刺、不累及面部以外区域以及存在潮红。面部皮脂腺肥大,有时伴有纤维化改变,可能导致皮肤难看地增厚。特别是男性,可能会出现鼻子明显肿大和变形。偶尔,酒渣鼻的主要特征是眼睑肿胀以及面部其他部位坚实的水肿性改变。眼睛受累是一种重要的、诊断不足的并发症,可能导致严重的眼部疾病。酒渣鼻累及眼外表面通常需要眼科建议。眼部酒渣鼻和皮肤酒渣鼻的程度之间通常没有关联,眼部酒渣鼻可能单独出现。酒渣鼻是一种毁容性疾病,会产生重大的心理社会影响,其对情绪健康和生活质量的有害影响常常被忽视。