Chalmers D A
Integrated Cardiovascular Therapeutics, Woodbury, N.Y., USA.
Nurse Pract. 1997 Oct;22(10):18, 23-8, 30.
Rosacea is a common facial dermatitis that currently affects an estimated 13 million Americans. It is a chronic and progressive cutaneous vascular disorder, primarily involving the malar and nasal areas of the face. Rosacea is characterized by flushing, erythema, papules, pustules, telanglectasia, facial edema, ocular lesions, and, in its most advanced and severe form, rhinophyma. Ocular lesions are common, including mild conjunctivitis, burning, and grittiness. Blepharitis, the most common ocular manifestation, is a nonulcerative condition of the lid margins. Rosacea most commonly occurs between the ages of 30 to 60, and may be seen in women experiencing hormonal changes associated with menopause. Women are more frequently affected than men; the most severe cases, however, are seen in men. Fair complexioned individuals of Northern European descent are most likely to be at risk for rosacea; most appear to be pre-disposed to flushing and blushing. Alcohol, stress, spicy foods, and extremes of temperature have all been implicated, but have not been found to actually cause rosacea. Early diagnosis by the primary care practitioner, management with systemic antibiotics such as tetracycline, and topical agents such as metronidazole, in conjunction with patient education and lifestyle modifications, can achieve remission in most instances.
酒渣鼻是一种常见的面部皮炎,目前估计影响着1300万美国人。它是一种慢性进行性皮肤血管疾病,主要累及面部的颊部和鼻部区域。酒渣鼻的特征包括潮红、红斑、丘疹、脓疱、毛细血管扩张、面部水肿、眼部病变,以及最严重的晚期表现——鼻赘。眼部病变很常见,包括轻度结膜炎、烧灼感和异物感。睑缘炎是最常见的眼部表现,是一种睑缘非溃疡性疾病。酒渣鼻最常发生在30至60岁之间,在经历与更年期相关的激素变化的女性中也可能出现。女性比男性更容易受到影响;然而,最严重的病例见于男性。北欧血统、肤色白皙的人最容易患酒渣鼻;大多数人似乎易出现脸红和潮热。酒精、压力、辛辣食物和极端温度都与之有关,但尚未发现它们实际上会导致酒渣鼻。初级保健医生进行早期诊断,使用四环素等全身性抗生素和甲硝唑等局部用药进行治疗,并结合患者教育和生活方式改变,在大多数情况下可以实现缓解。