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荷兰国家阑尾炎诊断指南中影像检查附加价值的前瞻性评估——我们是否忽略了临床洞察力?

Prospective evaluation of the added value of imaging within the Dutch National Diagnostic Appendicitis Guideline--do we forget our clinical eye?

作者信息

Schok Thomas, Simons Petra C G, Janssen-Heijnen Maryska L G, Peters Nathalie A L R, Konsten Joop L M

机构信息

Department of Surgery, VieCuri Medical Centre, Venlo, The Netherlands.

出版信息

Dig Surg. 2014;31(6):436-43. doi: 10.1159/000369587. Epub 2015 Jan 14.

Abstract

BACKGROUND

Annually 16,000 appendectomies are performed in the Netherlands, of which 15-20% are negative. In 2010, to reduce this unacceptable percentage of superfluous appendectomies, the Dutch Association for Surgery introduced the 'Appendicitis Guideline'. This guideline recommends the use of imaging. In this observational prospective study the added value of imaging in everyday clinical practice is evaluated.

METHODS

All patients with suspected appendicitis were included at the emergency department of a Dutch teaching hospital during the period from September 2011 to May 2012 (n = 350; 237 adults and 113 children under 18 years). Adherence to the guideline was evaluated.

RESULTS

75 Patients (21%) were not referred for imaging because of a low suspicion or alternative diagnosis. In 16 patients (5%) the guideline was not followed. Of the 259 patients (74%) who underwent ultrasonography, 105 (30%) also underwent computed tomography (CT). 127 appendectomies were performed, showing appendicitis in 112 patients (88%); 15 appendectomies (12%) were negative. In the latter group, 12 were performed after false positive imaging results, and 3 following inconclusive imaging results.

CONCLUSION

When using imaging in the diagnosis of appendicitis, the percentage of negative appendectomies remains close to the percentage declared as unacceptable by the publishers of the guideline.

摘要

背景

在荷兰,每年进行16000例阑尾切除术,其中15%-20%的手术结果为阴性。2010年,为降低这种不必要阑尾切除术的不可接受比例,荷兰外科学会推出了《阑尾炎指南》。该指南推荐使用影像学检查。在这项观察性前瞻性研究中,评估了影像学检查在日常临床实践中的附加价值。

方法

纳入2011年9月至2012年5月期间荷兰一家教学医院急诊科所有疑似阑尾炎的患者(n = 350;237名成人和113名18岁以下儿童)。评估对指南的遵循情况。

结果

75例患者(21%)因怀疑程度低或存在其他诊断而未接受影像学检查。16例患者(5%)未遵循指南。在259例接受超声检查的患者(74%)中,105例(30%)还接受了计算机断层扫描(CT)。共进行了127例阑尾切除术,112例患者(88%)显示患有阑尾炎;15例阑尾切除术(12%)结果为阴性。在后一组中,12例是在影像学检查结果呈假阳性后进行的,3例是在影像学检查结果不明确后进行的。

结论

在使用影像学检查诊断阑尾炎时,阴性阑尾切除术的比例仍接近该指南发布者宣称不可接受的比例。

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