Department of Surgery, OLVG, Amsterdam, The Netherlands.
Department of Surgery, OLVG, Amsterdam, The Netherlands.
J Pediatr Surg. 2018 Oct;53(10):2028-2031. doi: 10.1016/j.jpedsurg.2018.02.050. Epub 2018 Feb 17.
In children, the diagnosis “acute appendicitis” is difficult. In 2010, a new Dutch appendicitis guideline was published with the goal to reduce the negative appendectomy rate. The guideline recommended mandatory imaging (ultrasound first and CT or MRI when inconclusive) before surgery. This study examines whether the negative appendectomy rate in children has declined after the implementation of the guideline and if the number of ionising imaging procedures increased.
In this cohort study, all consecutive patients aged 17 or younger, with the suspicion of appendicitis were included. Patients were divided into two groups. Those who presented between 2006 and 2010 (before the implementation) and those between 2011 and 2016 (after implementation).
In total, 748 children were enrolled, of which 363 children were seen before and 385 children after implementation of the guideline. Before implementation, 46% of the children with acute appendicitis underwent preoperative ultrasound compared with 95% in the post implementation group, p < 0.001. Any imaging was performed in 51% and 100%, respectively, p < 0.001. The percentage of negative appendectomy before implementation was 13% and 2.7% after implementation, p < 0.001. There was no significant increase in the number of CT scans before and after the implementation of the guideline, 3.6% versus 6.0%, respectively, p = 0.126. There was no increase in direct medical costs.
Mandatory preoperative imaging in children with the suspicion of acute appendicitis results in a significant decrease in negative appendectomies with no increase in the number of CT scans and without a substantial increase in costs.
在儿童中,“急性阑尾炎”的诊断较为困难。2010 年,发布了新的荷兰阑尾炎指南,旨在降低阴性阑尾切除术率。该指南建议在手术前进行强制性影像学检查(首先进行超声检查,超声结果不确定时进行 CT 或 MRI 检查)。本研究旨在调查该指南实施后儿童的阴性阑尾切除术率是否降低,以及电离成像程序的数量是否增加。
在这项队列研究中,所有疑似阑尾炎且年龄在 17 岁以下的连续患者均被纳入研究。患者分为两组:一组在 2006 年至 2010 年(指南实施前)就诊,另一组在 2011 年至 2016 年(指南实施后)就诊。
共纳入 748 例儿童,其中 363 例在指南实施前就诊,385 例在指南实施后就诊。在指南实施前,46%的急性阑尾炎患儿接受了术前超声检查,而在指南实施后,这一比例上升至 95%,p<0.001。分别有 51%和 100%的患儿接受了任何影像学检查,p<0.001。在指南实施前,阴性阑尾切除术的比例为 13%,而在指南实施后,这一比例下降至 2.7%,p<0.001。在指南实施前后,CT 扫描的数量分别为 3.6%和 6.0%,无显著增加,p=0.126。直接医疗费用也没有增加。
在疑似急性阑尾炎的儿童中进行强制性术前影像学检查可显著降低阴性阑尾切除术的比例,同时不会增加 CT 扫描的数量,也不会显著增加成本。