Velázquez-Macías R F, Serena Serradell A, Hernández Pando R, Méndez Bognani M, Sánchez Montiel J A
Rev Gastroenterol Mex. 1989 Oct-Dec;54(4):231-7.
Four cases of familial polyposis coli (FPC), seen at Dr. Manuel Gea González General Hospital from 1985 to 1987, are presented. Three females and one male, with ages ranging between 23 and 52 years, are presented. The clinical picture included bloody feces, polyp prolapse, and a maxillary osteoma. In 3 cases the correct preoperative diagnosis was made by rectosigmoidoscopy, biopsy and barium enema. In one patient, urgently operated on, the diagnosis was postoperatively made by colonoscopy. The adenocarcinoma of the colon appeared associated with FPC in three cases (one of the mucinous variety). One total coloproctectomy and two abdominal colectomies with ileorectal anastomosis were performed. One patient operated on because of bowel obstruction was treated by right hemicolectomy. This case developed abdominal carcinomatosis afterwards. One woman died; another one was lost during follow-up, and the other one had no complications. The association of FPC and mucinous adenocarcinoma of the colon is reported for the first time.
本文介绍了1985年至1987年在曼努埃尔·盖亚·冈萨雷斯综合医院收治的4例家族性腺瘤性息肉病（FPC）患者。其中有3名女性和1名男性，年龄在23岁至52岁之间。临床表现包括便血、息肉脱垂和上颌骨骨瘤。3例患者通过直肠乙状结肠镜检查、活检和钡剂灌肠做出了正确的术前诊断。1例患者紧急手术，术后通过结肠镜检查做出诊断。3例患者的结肠癌（其中1例为黏液性癌）与FPC相关。实施了1例全结肠直肠切除术和2例腹部结肠切除术并进行回肠直肠吻合术。1例因肠梗阻接受手术的患者接受了右半结肠切除术治疗。该病例随后发生了腹部癌转移。1名女性死亡；另1名在随访期间失访，还有1名未出现并发症。首次报道了FPC与结肠黏液腺癌的关联。
