Hosomi M, Miyake O, Matsumiya K, Oka T, Takaha M, Kurata A
Department of Urology, Osaka National Hospital.
Hinyokika Kiyo. 1989 Nov;35(11):1981-4.
A 57-year-old Japanese man presented with a mass 3 cm in diameter at the root of the penis. The patient had noticed the mass growing for 5 years, but had no pain or itching. Histological examination revealed it to be invasive Paget's disease, and the mass was resected along with skin of normal appearance within 3 cm around it. Regional lymph node metastasis was also revealed in the operation, and irradiation at the pelvic and inguinal region was done. Extramammary Paget's disease with a large mass is relatively rare, and invasive extramammary Paget's disease has a poor prognosis.
一名57岁的日本男性患者阴茎根部出现一个直径3厘米的肿物。患者发现该肿物生长已有5年,但无疼痛或瘙痒症状。组织学检查显示为浸润性佩吉特病,遂将肿物连同其周围3厘米内外观正常的皮肤一并切除。手术中还发现有区域淋巴结转移,于是对盆腔和腹股沟区域进行了放疗。伴有巨大肿物的乳房外佩吉特病相对少见,浸润性乳房外佩吉特病预后较差。