肾细胞癌合并增殖性狼疮性肾炎。
Renal cell carcinoma with proliferative lupus nephritis.
作者信息
Wong Koh-Wei
机构信息
Department of Medicine, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia.
出版信息
BMJ Case Rep. 2015 Jan 16;2015:bcr2014208060. doi: 10.1136/bcr-2014-208060.
Abstract
We report a case of renal cell carcinoma diagnosed after a patient was treated successfully with intravenous cyclophosphamide for her active proliferative lupus nephritis (classes III and V). After the intravenous cyclophosphamide regimen, the patient was asymptomatic with persistent microscopic haematuria, and no proteinuria. The renal cell carcinoma was located on the left kidney; incidentally, this was where the initial renal biopsy was done to diagnose lupus nephritis.
摘要
我们报告一例肾细胞癌病例，该患者因活动性增殖性狼疮性肾炎（III 级和 V 级）接受静脉环磷酰胺治疗成功后被诊断出此病。在静脉注射环磷酰胺治疗方案后，患者无症状，仅有持续性镜下血尿，无蛋白尿。肾细胞癌位于左肾；巧合的是，此处正是当初进行肾活检以诊断狼疮性肾炎的部位。
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本文引用的文献
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2
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Best Pract Res Clin Rheumatol. 2009 Aug;23(4):539-47. doi: 10.1016/j.berh.2008.12.007.
3
Renal cell carcinoma associated immunosuppressive therapy: a case report with Wegener's granulomatosis.肾细胞癌相关免疫抑制治疗：一例伴有韦格纳肉芽肿病的病例报告。
Rheumatol Int. 2009 Nov;30(1):119-21. doi: 10.1007/s00296-009-0911-x.
4
Hematologic malignant neoplasms after drug exposure in rheumatoid arthritis.类风湿关节炎药物暴露后发生的血液系统恶性肿瘤
Arch Intern Med. 2008 Feb 25;168(4):378-81. doi: 10.1001/archinternmed.2007.107.
5
Malignancies and cyclophosphamide exposure in Wegener's granulomatosis.韦格纳肉芽肿病中的恶性肿瘤与环磷酰胺暴露
J Rheumatol. 2008 Jan;35(1):11-3.
6
Mycophenolate mofetil and risk of developing malignancy after orthotopic heart transplantation: analysis of the transplant registry of the International Society for Heart and Lung Transplantation.霉酚酸酯与原位心脏移植后发生恶性肿瘤的风险：国际心肺移植学会移植登记处分析
J Heart Lung Transplant. 2006 Oct;25(10):1186-91. doi: 10.1016/j.healun.2006.06.010. Epub 2006 Sep 18.
7
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Kidney Int. 2006 Sep;70(6):1182-6. doi: 10.1038/sj.ki.5001730. Epub 2006 Jul 26.
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