Lim Ki Hong, Jung Jin-Hee, Kwon Jae Hyun, Lee Yong Seok, Bae Jungbum, Cho Min Chul, Lee Kwang Soo, Lee Hae Won
Department of Urology, Dongguk University Ilsan Hospital, Goyang, Korea.
Department of Radiology, Dongguk University Ilsan Hospital, Goyang, Korea.
Korean J Urol. 2015 Jan;56(1):56-62. doi: 10.4111/kju.2015.56.1.56. Epub 2015 Jan 6.
The objective was to determine whether stone density on plain radiography (kidney-ureter-bladder, KUB) could predict the outcome of extracorporeal shockwave lithotripsy (ESWL) for ureteral stones.
A total of 223 patients treated by ESWL for radio-opaque ureteral stones of 5 to 20 mm were included in this retrospective study. All patients underwent routine blood and urine analyses, plain radiography (KUB), and noncontrast computed tomography (NCCT) before ESWL. Demographic, stone, and radiological characteristics on KUB and NCCT were analyzed. The patients were categorized into two groups: lower-density (LD) group (radiodensity less than or equal to that of the 12th rib, n=163) and higher-density (HD) group (radiodensity greater than that of the 12th rib, n=60). Stone-free status was assessed by KUB every week after ESWL. A successful outcome was defined as stone free within 1 month after ESWL.
Mean stone size in the LD group was significantly smaller than that in the HD group (7.5±1.4 mm compared with 9.9±2.9 mm, p=0.002). The overall success rates in the LD and HD groups were 82.1% and 60.0%, respectively (p=0.007). The mean duration of stone-free status and average number of SWL sessions required for success in the two groups were 21.7 compared with 39.2 days and 1.8 compared with 2.3, respectively (p<0.05). On multivariate logistic analysis, stone size and time to ESWL since colic and radiodensity of the stone on KUB were independent predictors of successful ESWL.
Our data suggest that larger stone size, longer time to ESWL, and ureteral stones with a radiodensity greater than that of the 12th rib may be at a relatively higher risk of ESWL failure 1 month after the procedure.
本研究旨在确定腹部平片(肾脏-输尿管-膀胱,KUB)上的结石密度能否预测输尿管结石体外冲击波碎石术(ESWL)的治疗效果。
本回顾性研究纳入了223例接受ESWL治疗的5至20mm不透X线输尿管结石患者。所有患者在ESWL治疗前均接受了常规血液和尿液分析、腹部平片(KUB)及非增强计算机断层扫描(NCCT)。分析了KUB和NCCT上的人口统计学、结石及影像学特征。患者被分为两组:低密度(LD)组(放射密度小于或等于第12肋,n = 163)和高密度(HD)组(放射密度大于第12肋,n = 60)。ESWL治疗后每周通过KUB评估结石清除情况。成功的定义为ESWL治疗后1个月内结石清除。
LD组的平均结石大小显著小于HD组(分别为7.5±1.4mm和9.9±2.9mm,p = 0.002)。LD组和HD组的总体成功率分别为82.1%和60.0%(p = 0.007)。两组结石清除状态的平均持续时间和成功所需的平均SWL治疗次数分别为21.7天和39.2天,以及1.8次和2.3次(p < 0.05)。多因素逻辑分析显示,结石大小、绞痛发作至ESWL的时间以及KUB上结石的放射密度是ESWL成功的独立预测因素。
我们的数据表明,较大的结石大小、较长的ESWL治疗时间以及放射密度大于第12肋的输尿管结石在ESWL治疗后1个月可能有相对较高的治疗失败风险。