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结石及患者特征对预测体外冲击波碎石成功率的影响:一项横断面研究。

The effect of stone and patient characteristics in predicting extra-corporal shock wave lithotripsy success rate: A cross sectional study.

作者信息

Al-Zubi Mohammad, Al Sleibi Ammar, Elayan Basel Mazen, Al-Issawi Subhi Zahi, Bani-Hani Morad, Alsharei Adel, AlSmadi Jad, Abualhaj Saleh, Ibrahim Ala' Y

机构信息

Department of Surgery, Urology Division, Faculty of Medicine, Yarmouk University, Irbid, Jordan.

Department of Clinical Sciences, Al-Balqa Applied University, Jordan.

出版信息

Ann Med Surg (Lond). 2021 Sep 10;70:102829. doi: 10.1016/j.amsu.2021.102829. eCollection 2021 Oct.

Abstract

INTRODUCTION

We determine the effect of patient characteristics (age, sex, and body mass index BMI) and stone characteristics (density, location, and size) by non-contrast computed tomography of the kidneys, ureters, and bladder (CT-KUB) in predicting the success of extracorporeal shock wave lithotripsy (ESWL) in the treatment of kidney and ureteric stones. We present this study to further enrich the knowledge of physicians towards the effect of different patient characteristics upon predicting extra-corporal shock wave lithotripsy success rates.

METHODS

We evaluated 155 patients who received ESWL for renal and ureteric stone measuring 3-20 mm (mm), over a 3-month period. The stone size in millimeters, density in Hounsfield units (HU) and its location was determined on pre-treatment CT-KUB. ESWL was successful if post-treatment residual renal stone fragments were ≤3 mm and for ureteric stones should be totally cleared.

RESULTS

The overall success of ESWL treatment was observed in 65.8% of the 155 patients. There was no significant difference seen when the effect of patients age, sex and BMI were studied with ESWL outcome with P values were 0.155, 0.101 and 0.415 respectively. Also, stone location either in the kidney or ureter has no statistically significant effect on ESWL response rate. while stone density and size determined on CT KUB have statistically significant effect on the success rate of ESWL with a P-value of 0.002 and 0.000 respectively.

CONCLUSIONS

This study shows that determination of stone density and stone size on CT KUB pre ESWL can help to predict the outcome of ESWL. We propose that stone density <500 HU and stone size < 5 mm are highly likely to result in successful ESWL.

摘要

引言

我们通过肾脏、输尿管和膀胱的非增强计算机断层扫描(CT-KUB)来确定患者特征(年龄、性别和体重指数BMI)以及结石特征(密度、位置和大小)对体外冲击波碎石术(ESWL)治疗肾和输尿管结石成功率的影响。我们开展这项研究是为了进一步丰富医生对于不同患者特征对预测体外冲击波碎石术成功率影响的认识。

方法

我们评估了155例在3个月期间接受ESWL治疗3-20毫米肾和输尿管结石的患者。在治疗前的CT-KUB上确定结石的毫米尺寸、亨氏单位(HU)密度及其位置。如果治疗后残留的肾结石碎片≤3毫米且输尿管结石完全清除,则ESWL治疗成功。

结果

155例患者中,ESWL治疗的总体成功率为65.8%。研究患者年龄、性别和BMI对ESWL结果的影响时,未发现显著差异,P值分别为0.155、0.101和0.415。此外,结石位于肾脏或输尿管对ESWL反应率没有统计学上的显著影响。而CT-KUB上确定的结石密度和大小对ESWL成功率有统计学上的显著影响,P值分别为0.002和0.000。

结论

本研究表明,在ESWL前通过CT-KUB确定结石密度和大小有助于预测ESWL的结果。我们提出,结石密度<500 HU且结石大小<5毫米很可能导致ESWL治疗成功。

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