Organic Chemistry Institute and Graduate School of Chemistry and Center for Soft Nanoscience, Westfälische Wilhelms-Universität Münster , Correnstrasse 40, 48149 Münster, Germany.
J Am Chem Soc. 2015 Feb 11;137(5):1967-71. doi: 10.1021/ja511963g. Epub 2015 Feb 2.
Polymer-shelled vesicles are prepared by using cyclodextrin vesicles as supramolecular templates and an adamantane-functionalized poly(acrylic acid) additive anchored via host-guest recognition, followed by cross-linking of carboxylic acid groups on the polymer. The polymer-shelled nanocontainers are highly stable and effective for encapsulating small hydrophilic molecules. We also show that a hollow cross-linked polymer cage can be obtained after dissolution of the template vesicles. The size and shell thickness of the polymer cage can be tuned by variation of template size and polymer length.
聚合物壳层囊泡是通过使用环糊精囊泡作为超分子模板和通过主客体识别锚定的金刚烷功能化的聚丙烯酸添加剂来制备的，然后通过聚合物上的羧酸基团的交联。聚合物壳层纳米容器高度稳定，可有效封装小分子亲水性分子。我们还表明，在模板囊泡溶解后可以获得中空交联聚合物笼。通过改变模板尺寸和聚合物长度可以调节聚合物笼的尺寸和壳厚度。
