Generation and characterization of a human monoclonal antibody against phenolic glycolipid-I of M. leprae.
作者信息
Moudgil K D, Gupta S K, Talwar G P
机构信息
Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
出版信息
Indian J Lepr. 1989 Oct;61(4):479-84.
PMID:2559933
Abstract
The development of an Epstein-Barr virus transformed human B-cell line secreting a monoclonal antibody (MoAb), KR2/B5 is described. KR2/B5 is an IgM type of antibody and is highly specific for phenolic glycolipid-I (PGL-I) a component unique to M. leprae. The MoAb appears to be directed against the terminal sugar residue of the immunodominant trisaccharide component of PGL-I.
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