采用酶联免疫吸附测定法检测麻风病患者中针对酚糖脂的抗体。
Detection of antibodies to phenolic glycolipid by ELISA in leprosy patients.
作者信息
Lal H, Jain V K, Mittal R A, Chaudhary S D, Saini V
机构信息
15/8FM Medical College, Rohtak.
出版信息
Indian J Lepr. 1993 Jan-Mar;65(1):95-9.
PMID:8463728
Abstract
Antibody (IgM) response to PGL-1, a surface glycolipid unique to Mycobacterium leprae has been studied in 25 cases each of lepromatous and tuberculoid leprosy and in 25 healthy controls. The absorbance value at 488 nm was expressed as antibody titre. Serum antibody titre was found to be significantly higher in patients than controls. Results confirm that antibody response in leprosy patients depend upon bacterial load.
摘要
对麻风分枝杆菌特有的一种表面糖脂酚糖脂-1（PGL-1）的抗体（IgM）反应，已在25例瘤型麻风、25例结核样型麻风患者以及25名健康对照者中进行了研究。488纳米处的吸光度值表示为抗体滴度。结果发现，患者的血清抗体滴度显著高于对照组。结果证实，麻风患者的抗体反应取决于细菌载量。
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